The mechanism of H171T resistance reveals the importance of Nδ-protonated His171 for the binding of allosteric inhibitor BI-D to HIV-1 integrase

Alison Slaughter, Kellie A. Jurado, Nanjie Deng, Lei Feng, Jacques J. Kessl, Nikoloz Shkriabai, Ross C. Larue, Hind J. Fadel, Pratiq A. Patel, Nivedita Jena, James R. Fuchs, Eric Poeschla, Ronald M. Levy, Alan Engelman, Mamuka Kvaratskhelia

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Medicine & Life Sciences