The management of cryptogenic fibrosing alveolitis in three regions of the United Kingdom

I. D.A. Johnston, S. A. Gomm, Sanjay Kalra, A. A. Woodcock, C. C. Evans, C. R.K. Hind

Research output: Contribution to journalArticle

64 Citations (Scopus)

Abstract

The case notes of 200 patients with cryptogenic fibrosing alveolitis, from three regions in the United Kingdom, were reviewed, in order to determine how physicians manage this uncommon condition. In the majority of cases (119), the diagnosis was based solely on clinical grounds, with no attempt at histological confirmation of the diagnosis. Transbronchial biopsy was attempted in 66 patients, but was unhelpful in confirming a diagnosis of pulmonary fibrosis in 30% of these patients. Thirty five patients underwent bronchoalveolar lavage, and 15 had an open lung biopsy. Of the 132 patients treated, 110 received prednisolone alone, and the rest a combination of other immunosuppressive agents. The doses and duration of therapy varied considerably. These results suggest that, in the late 1980s, there were wide variations of practice in the management of cryptogenic fibrosing alveolitis in the United Kingdom. This is likely to reflect a paucity of information on the optimum management of this uncommon condition.

Original languageEnglish (US)
Pages (from-to)891-893
Number of pages3
JournalEuropean Respiratory Journal
Volume6
Issue number6
StatePublished - Jan 1 1993
Externally publishedYes

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Idiopathic Pulmonary Fibrosis
Biopsy
Pulmonary Fibrosis
Practice Management
Bronchoalveolar Lavage
Immunosuppressive Agents
Prednisolone
United Kingdom
Physicians
Lung

Keywords

  • bronchoalveolar lavage
  • cryptogenic fibrosing alveolitis
  • transbronchial biopsy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Johnston, I. D. A., Gomm, S. A., Kalra, S., Woodcock, A. A., Evans, C. C., & Hind, C. R. K. (1993). The management of cryptogenic fibrosing alveolitis in three regions of the United Kingdom. European Respiratory Journal, 6(6), 891-893.

The management of cryptogenic fibrosing alveolitis in three regions of the United Kingdom. / Johnston, I. D.A.; Gomm, S. A.; Kalra, Sanjay; Woodcock, A. A.; Evans, C. C.; Hind, C. R.K.

In: European Respiratory Journal, Vol. 6, No. 6, 01.01.1993, p. 891-893.

Research output: Contribution to journalArticle

Johnston, IDA, Gomm, SA, Kalra, S, Woodcock, AA, Evans, CC & Hind, CRK 1993, 'The management of cryptogenic fibrosing alveolitis in three regions of the United Kingdom', European Respiratory Journal, vol. 6, no. 6, pp. 891-893.
Johnston IDA, Gomm SA, Kalra S, Woodcock AA, Evans CC, Hind CRK. The management of cryptogenic fibrosing alveolitis in three regions of the United Kingdom. European Respiratory Journal. 1993 Jan 1;6(6):891-893.
Johnston, I. D.A. ; Gomm, S. A. ; Kalra, Sanjay ; Woodcock, A. A. ; Evans, C. C. ; Hind, C. R.K. / The management of cryptogenic fibrosing alveolitis in three regions of the United Kingdom. In: European Respiratory Journal. 1993 ; Vol. 6, No. 6. pp. 891-893.
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