The London Classification of gastrointestinal neuromuscular pathology: Report on behalf of the gastro 2009 international working group

Charles H. Knowles, Roberto De Giorgio, Raj P. Kapur, Elisabeth Bruder, Gianrico Farrugia, Karel Geboes, Greger Lindberg, Joanne E. Martin, William A. Meier-Ruge, Peter J. Milla, Virpi V. Smith, Jean Marie Vandervinden, Béla Veress, Thilo Wedel

Research output: Contribution to journalArticlepeer-review

177 Scopus citations

Abstract

Objective: Guidelines on histopathological techniques and reporting for adult and paediatric gastrointestinal neuromuscular pathology have been produced recently by an international working group (IWG). These addressed the important but relatively neglected areas of histopathological practice of the general pathologist, including suction rectal biopsy and full-thickness intestinal tissue. Recommendations were presented for the indications, safe acquisition of tissue, histological techniques, reporting and referral of such histological material. Design: Consensual processes undertaken by the IWG and following established guideline decision group methodologies. Results and conclusion: This report presents a contemporary and structured classification of gastrointestinal neuromuscular pathology based on defined histopathological criteria derived from the existing guidelines. In recognition of its origins and first presentation in London at the World Congress of Gastroenterology 2009, this has been named 'The London Classification'. The implementation of this classification should allow some diagnostic standardisation, but should necessarily be viewed as a starting point for future modification as new data become available.

Original languageEnglish (US)
Pages (from-to)882-887
Number of pages6
JournalGut
Volume59
Issue number7
DOIs
StatePublished - Jul 2010

ASJC Scopus subject areas

  • Gastroenterology

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