TY - JOUR
T1 - The impact of Platelet Rich Plasma (PRP) in osseointegration of oral implants in dental panoramic radiography
T2 - Texture based evaluation
AU - Georgakopoulos, Ioannis
AU - Tsantis, Stavros
AU - Georgakopoulos, Panagiotis
AU - Korfiatis, Panagiotis
AU - Fanti, Elena
AU - Martelli, Marialaura
AU - Costaridou, Lena
AU - Petsas, Theodoros
AU - Panayiotakis, George
AU - Martelli, Francesco Saverio
PY - 2014
Y1 - 2014
N2 - Purpose. In this study the temporal texture differentiation associated with the bone formation properties, around loaded oral implants after Platelet Rich Plasma (PRP) employment, was investigated in Panoramic Radiographs. Materials and methods. Thirty eligible patients are randomly assigned to two groups. The test group received PRP application around new implants, while in the control group no PRP treatment was made. The bone-to-implant contact region was analyzed in a clinical sample of 60 Digitized Panoramic Radiographs, 30 corresponding to immediate implant loading (Class-I) and 30 after an 8 month follow-up period (Class-II). This region was sampled by 1146 circular Regions-of-Interest (ROIs), resulting from a specifically designed segmentation scheme based on Markov-Random-Fields (MRF). From each ROI, 41 textural features were extracted, then reduced to a subset of 4 features due to redundancy and employed as input to Receiver-Operating-Characteristic (ROC) analysis, to assess the textural differentiation between two classes. Results. The selected subset, achieved Area-Under- Curve (AUC) values ranging from 0.77-0.81 in the PRP group, indicating the significant temporal textural differentiation has been made. In the control group, the AUC values ranged from 0.56-0.68 demonstrating lesser osseo integration activity. Conclusion. This study provides evidences that PRP application may favor bone formation around loaded dental implants that could modify the dental treatment planning.
AB - Purpose. In this study the temporal texture differentiation associated with the bone formation properties, around loaded oral implants after Platelet Rich Plasma (PRP) employment, was investigated in Panoramic Radiographs. Materials and methods. Thirty eligible patients are randomly assigned to two groups. The test group received PRP application around new implants, while in the control group no PRP treatment was made. The bone-to-implant contact region was analyzed in a clinical sample of 60 Digitized Panoramic Radiographs, 30 corresponding to immediate implant loading (Class-I) and 30 after an 8 month follow-up period (Class-II). This region was sampled by 1146 circular Regions-of-Interest (ROIs), resulting from a specifically designed segmentation scheme based on Markov-Random-Fields (MRF). From each ROI, 41 textural features were extracted, then reduced to a subset of 4 features due to redundancy and employed as input to Receiver-Operating-Characteristic (ROC) analysis, to assess the textural differentiation between two classes. Results. The selected subset, achieved Area-Under- Curve (AUC) values ranging from 0.77-0.81 in the PRP group, indicating the significant temporal textural differentiation has been made. In the control group, the AUC values ranged from 0.56-0.68 demonstrating lesser osseo integration activity. Conclusion. This study provides evidences that PRP application may favor bone formation around loaded dental implants that could modify the dental treatment planning.
KW - Dental implants
KW - Implant segmentation
KW - Markov Random Fields
KW - Medical image texture analysis
KW - Platelet Rich Plasma
KW - Radiography
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U2 - 10.11138/ccmbm/2014.11.1.059
DO - 10.11138/ccmbm/2014.11.1.059
M3 - Article
AN - SCOPUS:84904266798
SN - 1724-8914
VL - 11
SP - 59
EP - 66
JO - Clinical Cases in Mineral and Bone Metabolism
JF - Clinical Cases in Mineral and Bone Metabolism
IS - 1
ER -