The immunobiology of muscle

Reinhard Hohlfeld, Andrew G. Engel

Research output: Contribution to journalArticle

258 Scopus citations

Abstract

Skeletal muscle can be both the site and target of immune reactions. Here, Reinhard Hohlfeld and Andrew Engel consider the role of muscle as an immunological microenvironment and discuss the immunological properties of human muscle cells. Furthermore, they provide a brief overview of autoimmune diseases of muscle and of other conditions in which intramuscular immune reactions play a role. Finally, they discuss the immunological problems of novel gene therapies that rely on muscle cells as vehicles for gene transfer.

Original languageEnglish (US)
Pages (from-to)269-274
Number of pages6
JournalImmunology Today
Volume15
Issue number6
DOIs
StatePublished - Jun 1994

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ASJC Scopus subject areas

  • Immunology

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