The Heart in Hypertension

Edward D. Frohlich; Carl Apstein; Aram V. Chobanian; Richard B. Devereux; Harriet P. Dustan; Victor Dzau; Fetnat Fauad-Tarazi; Michael J. Horan; Melvin Marcus; Barry Massie; Marc A. Pfeffer; Richard N. re; Edward J. Roccella; Daniel Savage; Clarence Shub

doi:10.1056/NEJM199210013271406

The Heart in Hypertension

Edward D. Frohlich, Carl Apstein, Aram V. Chobanian, Richard B. Devereux, Harriet P. Dustan, Victor Dzau, Fetnat Fauad-Tarazi, Michael J. Horan, Melvin Marcus, Barry Massie, Marc A. Pfeffer, Richard N. re, Edward J. Roccella, Daniel Savage, Clarence Shub

Cardiovascular Medicine

Research output: Contribution to journal › Review article › peer-review

577 Scopus citations

Abstract

HYPERTENSIVE heart disease can be defined as the response of the heart to the afterload imposed on the left ventricle by the progressively increasing arterial pressure and total peripheral resistance produced by hypertensive vascular disease. Although the response sometimes appears to be out of proportion to the level of the arterial pressure, it is primarily the result of the hemodynamic overload. Hypertension can cause or is related to various cardiac manifestations, among them left ventricular hypertrophy, congestive heart failure, cardiac dysrhythmias, and ischemic heart disease. Although the risk of atherosclerotic coronary heart disease is related to the systolic and diastolic…

Original language	English (US)
Pages (from-to)	998-1008
Number of pages	11
Journal	New England Journal of Medicine
Volume	327
Issue number	14
DOIs	https://doi.org/10.1056/NEJM199210013271406
State	Published - Oct 1 1992

ASJC Scopus subject areas

Medicine(all)

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10.1056/NEJM199210013271406

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title = "The Heart in Hypertension",

abstract = "HYPERTENSIVE heart disease can be defined as the response of the heart to the afterload imposed on the left ventricle by the progressively increasing arterial pressure and total peripheral resistance produced by hypertensive vascular disease. Although the response sometimes appears to be out of proportion to the level of the arterial pressure, it is primarily the result of the hemodynamic overload. Hypertension can cause or is related to various cardiac manifestations, among them left ventricular hypertrophy, congestive heart failure, cardiac dysrhythmias, and ischemic heart disease. Although the risk of atherosclerotic coronary heart disease is related to the systolic and diastolic…",

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AU - Frohlich, Edward D.

AU - Apstein, Carl

AU - Chobanian, Aram V.

AU - Devereux, Richard B.

AU - Dustan, Harriet P.

AU - Dzau, Victor

AU - Fauad-Tarazi, Fetnat

AU - Horan, Michael J.

AU - Marcus, Melvin

AU - Massie, Barry

AU - Pfeffer, Marc A.

AU - re, Richard N.

AU - Roccella, Edward J.

AU - Savage, Daniel

AU - Shub, Clarence

PY - 1992/10/1

Y1 - 1992/10/1

N2 - HYPERTENSIVE heart disease can be defined as the response of the heart to the afterload imposed on the left ventricle by the progressively increasing arterial pressure and total peripheral resistance produced by hypertensive vascular disease. Although the response sometimes appears to be out of proportion to the level of the arterial pressure, it is primarily the result of the hemodynamic overload. Hypertension can cause or is related to various cardiac manifestations, among them left ventricular hypertrophy, congestive heart failure, cardiac dysrhythmias, and ischemic heart disease. Although the risk of atherosclerotic coronary heart disease is related to the systolic and diastolic…

AB - HYPERTENSIVE heart disease can be defined as the response of the heart to the afterload imposed on the left ventricle by the progressively increasing arterial pressure and total peripheral resistance produced by hypertensive vascular disease. Although the response sometimes appears to be out of proportion to the level of the arterial pressure, it is primarily the result of the hemodynamic overload. Hypertension can cause or is related to various cardiac manifestations, among them left ventricular hypertrophy, congestive heart failure, cardiac dysrhythmias, and ischemic heart disease. Although the risk of atherosclerotic coronary heart disease is related to the systolic and diastolic…

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The Heart in Hypertension

Abstract

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