The genetics of ischaemic stroke

M. Matarin, A. Singleton, J. Hardy, J. Meschia

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Abstract

Matarin M, Singleton A, Hardy J, Meschia J (Laboratory of Neurogenetics, Bethesda, MD, USA; UCL Institute of Neurology, London, UK; Mayo Clinic, Jacksonville, FL, USA). The genetics of ischaemic stroke (Review). J Intern Med 2010; 267: 139-155. In this review, we discuss the genetic factors in both the aetiology and treatment of ischaemic stroke. We discuss candidate gene association studies, family linkage studies and the more recent whole genome association studies and whole genome expression studies. We also briefly discuss genetic testing for stroke risk and genetic analysis of treatment complications.

Original languageEnglish (US)
Pages (from-to)139-155
Number of pages17
JournalJournal of Internal Medicine
Volume267
Issue number2
DOIs
StatePublished - Feb 1 2010

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Keywords

  • Genetics
  • Genomics
  • Ischaemic stroke
  • Pharmacogenomics

ASJC Scopus subject areas

  • Internal Medicine

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