TY - JOUR
T1 - The genetics of ischaemic stroke
AU - Matarin, M.
AU - Singleton, A.
AU - Hardy, J.
AU - Meschia, J.
PY - 2010/2
Y1 - 2010/2
N2 - Matarin M, Singleton A, Hardy J, Meschia J (Laboratory of Neurogenetics, Bethesda, MD, USA; UCL Institute of Neurology, London, UK; Mayo Clinic, Jacksonville, FL, USA). The genetics of ischaemic stroke (Review). J Intern Med 2010; 267: 139-155. In this review, we discuss the genetic factors in both the aetiology and treatment of ischaemic stroke. We discuss candidate gene association studies, family linkage studies and the more recent whole genome association studies and whole genome expression studies. We also briefly discuss genetic testing for stroke risk and genetic analysis of treatment complications.
AB - Matarin M, Singleton A, Hardy J, Meschia J (Laboratory of Neurogenetics, Bethesda, MD, USA; UCL Institute of Neurology, London, UK; Mayo Clinic, Jacksonville, FL, USA). The genetics of ischaemic stroke (Review). J Intern Med 2010; 267: 139-155. In this review, we discuss the genetic factors in both the aetiology and treatment of ischaemic stroke. We discuss candidate gene association studies, family linkage studies and the more recent whole genome association studies and whole genome expression studies. We also briefly discuss genetic testing for stroke risk and genetic analysis of treatment complications.
KW - Genetics
KW - Genomics
KW - Ischaemic stroke
KW - Pharmacogenomics
UR - http://www.scopus.com/inward/record.url?scp=74849123824&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=74849123824&partnerID=8YFLogxK
U2 - 10.1111/j.1365-2796.2009.02202.x
DO - 10.1111/j.1365-2796.2009.02202.x
M3 - Article
C2 - 20175863
AN - SCOPUS:74849123824
SN - 0954-6820
VL - 267
SP - 139
EP - 155
JO - Journal of Internal Medicine
JF - Journal of Internal Medicine
IS - 2
ER -