The genetics of ischaemic stroke

M. Matarin, A. Singleton, J. Hardy, James F Meschia

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Matarin M, Singleton A, Hardy J, Meschia J (Laboratory of Neurogenetics, Bethesda, MD, USA; UCL Institute of Neurology, London, UK; Mayo Clinic, Jacksonville, FL, USA). The genetics of ischaemic stroke (Review). J Intern Med 2010; 267: 139-155. In this review, we discuss the genetic factors in both the aetiology and treatment of ischaemic stroke. We discuss candidate gene association studies, family linkage studies and the more recent whole genome association studies and whole genome expression studies. We also briefly discuss genetic testing for stroke risk and genetic analysis of treatment complications.

Original languageEnglish (US)
Pages (from-to)139-155
Number of pages17
JournalJournal of Internal Medicine
Volume267
Issue number2
DOIs
StatePublished - Feb 2010

Fingerprint

Stroke
Genome-Wide Association Study
Genetic Testing
Genetic Association Studies
Neurology
Genome

Keywords

  • Genetics
  • Genomics
  • Ischaemic stroke
  • Pharmacogenomics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

The genetics of ischaemic stroke. / Matarin, M.; Singleton, A.; Hardy, J.; Meschia, James F.

In: Journal of Internal Medicine, Vol. 267, No. 2, 02.2010, p. 139-155.

Research output: Contribution to journalArticle

Matarin, M. ; Singleton, A. ; Hardy, J. ; Meschia, James F. / The genetics of ischaemic stroke. In: Journal of Internal Medicine. 2010 ; Vol. 267, No. 2. pp. 139-155.
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