The frequency and diagnostic significance of periostitis in chondroblastoma

A. C. Brower, R. P. Moser, M. J. Kransdorf

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

A study was performed to determine the frequency of periosteal reaction associated with chondroblastoma, to investigate the underlying pathophysiology of the periosteal reaction, and to postulate the clinical importance of this radiographic observation. Two hundred fourteen histologically proved chondroblastomas were reviewed and observed for the presence or absence of periosteal reaction and for radiographic changes that might explain the cause of the periosteal reaction. A similar review was performed on 30 other epiphyseally centered lesions of various causes. A distinctive thick, solid periosteal reaction distal to the chondroblastoma was present in 47% of all chondroblastomas and 57% of chondroblastomas present in long bones (excluding the greater trochanter). No periosteal reaction was observed in any of the 30 epiphyseally centered lesions of other causes. When available for observation, plain films showed inflammatory changes in the joint surrounding the chondroblastoma, bone scintigraphy showed tracer uptake similar to that observed in inflammatory lesions and aggressive neoplasms, and MR images showed change in the marrow surrounding the chondroblastoma consistent with edema. This suggests an inflammatory reaction to the chondroblastoma, rather than mechanical stress across a weakened epiphysis, as the cause of the periostitis. We conclude that frequently the chondroblastoma produces a distinctive thick solid or layered periosteal response distant from the lesions along the diametaphyseal shaft. Observation of this unique periosteal response may help to distinguish chondroblastoma from other epiphyseally centered lesions.

Original languageEnglish (US)
Pages (from-to)309-314
Number of pages6
JournalAmerican Journal of Roentgenology
Volume154
Issue number2
StatePublished - 1990
Externally publishedYes

Fingerprint

Chondroblastoma
Periostitis
Observation
Bone and Bones
Mechanical Stress
Epiphyses
Motion Pictures
Radionuclide Imaging
Femur
Edema
Joints
Bone Marrow

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Brower, A. C., Moser, R. P., & Kransdorf, M. J. (1990). The frequency and diagnostic significance of periostitis in chondroblastoma. American Journal of Roentgenology, 154(2), 309-314.

The frequency and diagnostic significance of periostitis in chondroblastoma. / Brower, A. C.; Moser, R. P.; Kransdorf, M. J.

In: American Journal of Roentgenology, Vol. 154, No. 2, 1990, p. 309-314.

Research output: Contribution to journalArticle

Brower, AC, Moser, RP & Kransdorf, MJ 1990, 'The frequency and diagnostic significance of periostitis in chondroblastoma', American Journal of Roentgenology, vol. 154, no. 2, pp. 309-314.
Brower, A. C. ; Moser, R. P. ; Kransdorf, M. J. / The frequency and diagnostic significance of periostitis in chondroblastoma. In: American Journal of Roentgenology. 1990 ; Vol. 154, No. 2. pp. 309-314.
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