The expanding spectrum of Mycobacterium avium complex-associated pulmonary disease

E. Andrew Waller, Archana Roy, Lisa Brumble, Andras Khoor, Margaret M. Johnson, Jeffrey L. Garland

Research output: Contribution to journalArticle

32 Scopus citations

Abstract

Nontuberculous mycobacteria (NTM) are increasingly recognized as important pulmonary pathogens. Mycobacterium avium intracellulare complex (MAC) causes most lung infections due to NTM. Patients with preexisting lung disease or immunodeficiency are at greatest risk for developing MAC infection. The majority of MAC pulmonary cases, however, occur in immunocompetent elderly women in association with nodular infiltrates and bronchiectasis. More recently, pulmonary disease has also been described in immunocompetent patients after exposure to MAC-contaminated hot tubs. We describe a case of aggressive MAC lung disease in a young immunocompetent female patient without preexisting lung disease whose clinical and pathologic characteristics do not fit into any of these categories and may represent a unique manifestation of MAC lung disease.

Original languageEnglish (US)
Pages (from-to)1234-1241
Number of pages8
JournalChest
Volume130
Issue number4
DOIs
StatePublished - Oct 2006

Keywords

  • Hot tub lung
  • Mycobacterium avium complex
  • Nontuberculous mycobacterium

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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