The epidemiology of venous thromboembolism

John A. Heit, Frederick A. Spencer, Richard H. White

Research output: Contribution to journalArticle

284 Scopus citations

Abstract

Venous thromboembolism (VTE) is categorized by the U.S. Surgeon General as a major public health problem. VTE is relatively common and associated with reduced survival and substantial health-care costs, and recurs frequently. VTE is a complex (multifactorial) disease, involving interactions between acquired or inherited predispositions to thrombosis and VTE risk factors, including increasing patient age and obesity, hospitalization for surgery or acute illness, nursing-home confinement, active cancer, trauma or fracture, immobility or leg paresis, superficial vein thrombosis, and, in women, pregnancy and puerperium, oral contraception, and hormone therapy. Although independent VTE risk factors and predictors of VTE recurrence have been identified, and effective primary and secondary prophylaxis is available, the occurrence of VTE seems to be relatively constant, or even increasing.

Original languageEnglish (US)
Pages (from-to)3-14
Number of pages12
JournalJournal of Thrombosis and Thrombolysis
Volume41
Issue number1
DOIs
StatePublished - Jan 1 2016

Keywords

  • Deep vein thrombosis
  • Epidemiology
  • Pulmonary embolism
  • Thrombophlebitis
  • Venous thromboembolism

ASJC Scopus subject areas

  • Hematology
  • Cardiology and Cardiovascular Medicine

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