Abstract
Epidemiological studies increasingly inform Alzheimer's disease (AD) public health impact, prevention strategies, drug targets, therapeutic interventions, and clinical trial design. For this reason, the Alzheimer's Association Research Roundtable convened an international group of AD experts with experience in conducting both observational and clinical trials for a meeting on October 19 and 20, 2010, in Washington, DC, to discuss the role of epidemiologic studies in AD research and therapeutic advances. Topics included wellness markers and risk factors, with a focus on special populations such as those at elevated risk, super agers, and underserved populations. Discussions also highlighted lessons learned from observational studies of aging, cardiovascular disease, and other disease areas, as well as how new technologies have enabled the gathering of data relevant to drug development and clinical trial conduct.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 237-242 |
| Number of pages | 6 |
| Journal | Alzheimer's and Dementia |
| Volume | 8 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 2012 |
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Keywords
- Aging
- Alzheimer's disease
- Dementia
- Epidemiology
- Mild cognitive impairment
ASJC Scopus subject areas
- Health Policy
- Epidemiology
- Geriatrics and Gerontology
- Psychiatry and Mental health
- Cellular and Molecular Neuroscience
- Developmental Neuroscience
- Clinical Neurology
Cite this
The epidemiology of Alzheimer's disease : Laying the foundation for drug design, conduct, and analysis of clinical trials. / Yaffe, Kristine; Tocco, Michael; Petersen, Ronald Carl; Sigler, Catherine; Burns, Leah C.; Cornelius, Christel; Khachaturian, Ara S.; Irizarry, Michael C.; Carrillo, Maria C.
In: Alzheimer's and Dementia, Vol. 8, No. 3, 05.2012, p. 237-242.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The epidemiology of Alzheimer's disease
T2 - Laying the foundation for drug design, conduct, and analysis of clinical trials
AU - Yaffe, Kristine
AU - Tocco, Michael
AU - Petersen, Ronald Carl
AU - Sigler, Catherine
AU - Burns, Leah C.
AU - Cornelius, Christel
AU - Khachaturian, Ara S.
AU - Irizarry, Michael C.
AU - Carrillo, Maria C.
PY - 2012/5
Y1 - 2012/5
N2 - Epidemiological studies increasingly inform Alzheimer's disease (AD) public health impact, prevention strategies, drug targets, therapeutic interventions, and clinical trial design. For this reason, the Alzheimer's Association Research Roundtable convened an international group of AD experts with experience in conducting both observational and clinical trials for a meeting on October 19 and 20, 2010, in Washington, DC, to discuss the role of epidemiologic studies in AD research and therapeutic advances. Topics included wellness markers and risk factors, with a focus on special populations such as those at elevated risk, super agers, and underserved populations. Discussions also highlighted lessons learned from observational studies of aging, cardiovascular disease, and other disease areas, as well as how new technologies have enabled the gathering of data relevant to drug development and clinical trial conduct.
AB - Epidemiological studies increasingly inform Alzheimer's disease (AD) public health impact, prevention strategies, drug targets, therapeutic interventions, and clinical trial design. For this reason, the Alzheimer's Association Research Roundtable convened an international group of AD experts with experience in conducting both observational and clinical trials for a meeting on October 19 and 20, 2010, in Washington, DC, to discuss the role of epidemiologic studies in AD research and therapeutic advances. Topics included wellness markers and risk factors, with a focus on special populations such as those at elevated risk, super agers, and underserved populations. Discussions also highlighted lessons learned from observational studies of aging, cardiovascular disease, and other disease areas, as well as how new technologies have enabled the gathering of data relevant to drug development and clinical trial conduct.
KW - Aging
KW - Alzheimer's disease
KW - Dementia
KW - Epidemiology
KW - Mild cognitive impairment
UR - http://www.scopus.com/inward/record.url?scp=84860447272&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860447272&partnerID=8YFLogxK
U2 - 10.1016/j.jalz.2011.12.005
DO - 10.1016/j.jalz.2011.12.005
M3 - Article
C2 - 22546356
AN - SCOPUS:84860447272
VL - 8
SP - 237
EP - 242
JO - Alzheimer's and Dementia
JF - Alzheimer's and Dementia
SN - 1552-5260
IS - 3
ER -