The electrophysiology of the motor neuron diseases

Research output: Contribution to journalReview article

7 Scopus citations

Abstract

The motor neuron diseases are a set of disorders associated with the selective degeneration of motor neurons. Amyotrophic lateral sclerosis (ALS) is the most common and confers the gravest prognosis. Although ALS occurs with known genetic causes in a small minority, other motor neuron disorders have well-defined genetic mutations. Electrodiagnostic testing is important to distinguish these various disorders. Electrodiagnostic testing is also crucial for distinguishing potential mimic syndromes, such as multifocal motor neuropathy and inclusion body myositis. Newer neurophysiology techniques have been developed in the past several years. What role these techniques will play in clinical practice is currently unknown.

Original languageEnglish (US)
Pages (from-to)605-620
Number of pages16
JournalNeurologic clinics
Volume30
Issue number2
DOIs
StatePublished - May 1 2012

Keywords

  • Amyotrophic lateral sclerosis
  • El Escorial criteria
  • Multifocal motor neuropathy
  • Primary lateral sclerosis
  • Progressive muscular atrophy
  • Spinal muscular atrophy

ASJC Scopus subject areas

  • Clinical Neurology

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