The effects of direct inhibition of geranylgeranyl pyrophosphate synthase on osteoblast differentiation

Medicine & Life Sciences

• Geranylgeranyl-Diphosphate Geranylgeranyltransferase 100%
• digeranyl bisphosphonate 68%
• Osteoblasts 47%
• geranylgeranyl pyrophosphate 32%
• farnesyl pyrophosphate 23%
• Farnesyltranstransferase 22%
• Hydroxymethylglutaryl-CoA Reductase Inhibitors 9%
• Prenylation 6%
• Terpenes 6%
• Glucocorticoid Receptors 5%
• Osteocalcin 5%
• Cytoplasmic and Nuclear Receptors 5%
• Alkaline Phosphatase 4%
• Osteogenesis 4%
• Cholesterol 3%
• Serum 2%
• Pharmaceutical Preparations 2%

Chemical Compounds

• Hydroxymethylglutaryl Coenzyme A Reductase Inhibitor 71%
• Glucocorticoid 63%
• Isoprenoid 63%
• Hormone 49%
• Cholesterol 44%
• Time 17%