The effect of obstructive sleep apnea on amputation site healing

Karen L. Andrews, Mansour Dib, Thomas C. Shives, Tanya L. Hoskin, David A. Liedl, Andrea Boon

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Obstructive sleep apnea (OSA) is an independent risk for hypertension, cerebral artery stenosis, stroke and hypercoagulability. 1 Our research objective was to assess whether sleep disordered breathing affects the peripheral circulation, decreases perfusion as measured by TcPO2 and decreases the odds that a partial-foot amputation site will heal. We hypothesized that OSA would be an independent risk factor causing delayed healing of partial-foot amputations. We conducted a retrospective, observational study on a total of 307 patients who had TcPO2 measurements and underwent partial-foot amputation. Twenty-five of these patients had OSA. In our study, patients with OSA had a 3.7-fold increase in odds of healing within 3 months in comparison with patients without OSA. Of note, 16 patients (64%) with OSA were not treated with continuous positive airway pressure (CPAP) and healed within 3 months. Our results do not support our hypothesis that the presence of sleep apnea may impair healing of partial foot amputations. Further studies are needed to fully determine the effect of OSA and its treatment on TcPO2s and healing.

Original languageEnglish (US)
Pages (from-to)61-63
Number of pages3
JournalJournal of Vascular Nursing
Volume30
Issue number2
DOIs
StatePublished - Jun 2012

Fingerprint

Obstructive Sleep Apnea
Amputation
Foot
Sleep Apnea Syndromes
Continuous Positive Airway Pressure
Cerebral Arteries
Thrombophilia
Observational Studies
Pathologic Constriction
Retrospective Studies
Perfusion
Stroke
Hypertension
Research

ASJC Scopus subject areas

  • Medical–Surgical

Cite this

The effect of obstructive sleep apnea on amputation site healing. / Andrews, Karen L.; Dib, Mansour; Shives, Thomas C.; Hoskin, Tanya L.; Liedl, David A.; Boon, Andrea.

In: Journal of Vascular Nursing, Vol. 30, No. 2, 06.2012, p. 61-63.

Research output: Contribution to journalArticle

Andrews, Karen L. ; Dib, Mansour ; Shives, Thomas C. ; Hoskin, Tanya L. ; Liedl, David A. ; Boon, Andrea. / The effect of obstructive sleep apnea on amputation site healing. In: Journal of Vascular Nursing. 2012 ; Vol. 30, No. 2. pp. 61-63.
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