The effect of corneal light scatter on vision after descemet stripping with endothelial keratoplasty

Sanjay V. Patel, Keith Baratz, David O. Hodge, Leo J. Maguire, Jay W. McLaren

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Objective: To establish an association between corneal light scatter and vision after Descemet stripping with endothelial keratoplasty (DSEK). Methods: Twenty eyes of patients with Fuchs endothelial dystrophy were examined before and at 1,3, and 6 months after DSEK in a prospective study. Main outcome measures were high-contrast best-corrected visual acuity, intraocular forward light scatter, and corneal backscatter. Results: One eye was excluded because of endothelial graft failure within 1 month. Best-corrected visual acuity improved at 3 months after DSEK (mean [standard deviation], 0.31 [0.20] logarithm of the minimum angle of resolution [logMAR]; Snellen equivalent, 20/41) relative to before DSEK (0.46 [0.26] logMAR; Snellen equiva-lent, 20/58; P = .03). Posterior corneal backscatter decreased 1 month after DSEK (P< .001), but backscatter from the anterior, middle, and posterior cornea did not return to normal by 6 months (P≤ .02). At 6 months, best-corrected visual acuity correlated with recipient age (r = 0.84, P < .001) and with intraocular forward light scatter (r =0.67, P< .001); forward light scatter also correlated with recipient age (r=0.67, P< .001). Conclusions: Six months after DSEK, corneal light scatter remained greater in eyes with Fuchs endothelial dystrophy than in normal eyes and correlated with recipient age and visual acuity. Recipient age might be the best preoperative predictor of vision after DSEK.

Original languageEnglish (US)
Pages (from-to)153-160
Number of pages8
JournalArchives of Ophthalmology
Volume127
Issue number2
DOIs
StatePublished - Feb 2009

Fingerprint

Descemet Stripping Endothelial Keratoplasty
Light
Visual Acuity
Fuchs' Endothelial Dystrophy
Cornea
Outcome Assessment (Health Care)
Prospective Studies
Transplants

ASJC Scopus subject areas

  • Ophthalmology

Cite this

The effect of corneal light scatter on vision after descemet stripping with endothelial keratoplasty. / Patel, Sanjay V.; Baratz, Keith; Hodge, David O.; Maguire, Leo J.; McLaren, Jay W.

In: Archives of Ophthalmology, Vol. 127, No. 2, 02.2009, p. 153-160.

Research output: Contribution to journalArticle

Patel, Sanjay V. ; Baratz, Keith ; Hodge, David O. ; Maguire, Leo J. ; McLaren, Jay W. / The effect of corneal light scatter on vision after descemet stripping with endothelial keratoplasty. In: Archives of Ophthalmology. 2009 ; Vol. 127, No. 2. pp. 153-160.
@article{8f4646f529fb45f881cadc05bd29b19d,
title = "The effect of corneal light scatter on vision after descemet stripping with endothelial keratoplasty",
abstract = "Objective: To establish an association between corneal light scatter and vision after Descemet stripping with endothelial keratoplasty (DSEK). Methods: Twenty eyes of patients with Fuchs endothelial dystrophy were examined before and at 1,3, and 6 months after DSEK in a prospective study. Main outcome measures were high-contrast best-corrected visual acuity, intraocular forward light scatter, and corneal backscatter. Results: One eye was excluded because of endothelial graft failure within 1 month. Best-corrected visual acuity improved at 3 months after DSEK (mean [standard deviation], 0.31 [0.20] logarithm of the minimum angle of resolution [logMAR]; Snellen equivalent, 20/41) relative to before DSEK (0.46 [0.26] logMAR; Snellen equiva-lent, 20/58; P = .03). Posterior corneal backscatter decreased 1 month after DSEK (P< .001), but backscatter from the anterior, middle, and posterior cornea did not return to normal by 6 months (P≤ .02). At 6 months, best-corrected visual acuity correlated with recipient age (r = 0.84, P < .001) and with intraocular forward light scatter (r =0.67, P< .001); forward light scatter also correlated with recipient age (r=0.67, P< .001). Conclusions: Six months after DSEK, corneal light scatter remained greater in eyes with Fuchs endothelial dystrophy than in normal eyes and correlated with recipient age and visual acuity. Recipient age might be the best preoperative predictor of vision after DSEK.",
author = "Patel, {Sanjay V.} and Keith Baratz and Hodge, {David O.} and Maguire, {Leo J.} and McLaren, {Jay W.}",
year = "2009",
month = "2",
doi = "10.1001/archophthalmol.2008.581",
language = "English (US)",
volume = "127",
pages = "153--160",
journal = "JAMA Ophthalmology",
issn = "2168-6165",
publisher = "American Medical Association",
number = "2",

}

TY - JOUR

T1 - The effect of corneal light scatter on vision after descemet stripping with endothelial keratoplasty

AU - Patel, Sanjay V.

AU - Baratz, Keith

AU - Hodge, David O.

AU - Maguire, Leo J.

AU - McLaren, Jay W.

PY - 2009/2

Y1 - 2009/2

N2 - Objective: To establish an association between corneal light scatter and vision after Descemet stripping with endothelial keratoplasty (DSEK). Methods: Twenty eyes of patients with Fuchs endothelial dystrophy were examined before and at 1,3, and 6 months after DSEK in a prospective study. Main outcome measures were high-contrast best-corrected visual acuity, intraocular forward light scatter, and corneal backscatter. Results: One eye was excluded because of endothelial graft failure within 1 month. Best-corrected visual acuity improved at 3 months after DSEK (mean [standard deviation], 0.31 [0.20] logarithm of the minimum angle of resolution [logMAR]; Snellen equivalent, 20/41) relative to before DSEK (0.46 [0.26] logMAR; Snellen equiva-lent, 20/58; P = .03). Posterior corneal backscatter decreased 1 month after DSEK (P< .001), but backscatter from the anterior, middle, and posterior cornea did not return to normal by 6 months (P≤ .02). At 6 months, best-corrected visual acuity correlated with recipient age (r = 0.84, P < .001) and with intraocular forward light scatter (r =0.67, P< .001); forward light scatter also correlated with recipient age (r=0.67, P< .001). Conclusions: Six months after DSEK, corneal light scatter remained greater in eyes with Fuchs endothelial dystrophy than in normal eyes and correlated with recipient age and visual acuity. Recipient age might be the best preoperative predictor of vision after DSEK.

AB - Objective: To establish an association between corneal light scatter and vision after Descemet stripping with endothelial keratoplasty (DSEK). Methods: Twenty eyes of patients with Fuchs endothelial dystrophy were examined before and at 1,3, and 6 months after DSEK in a prospective study. Main outcome measures were high-contrast best-corrected visual acuity, intraocular forward light scatter, and corneal backscatter. Results: One eye was excluded because of endothelial graft failure within 1 month. Best-corrected visual acuity improved at 3 months after DSEK (mean [standard deviation], 0.31 [0.20] logarithm of the minimum angle of resolution [logMAR]; Snellen equivalent, 20/41) relative to before DSEK (0.46 [0.26] logMAR; Snellen equiva-lent, 20/58; P = .03). Posterior corneal backscatter decreased 1 month after DSEK (P< .001), but backscatter from the anterior, middle, and posterior cornea did not return to normal by 6 months (P≤ .02). At 6 months, best-corrected visual acuity correlated with recipient age (r = 0.84, P < .001) and with intraocular forward light scatter (r =0.67, P< .001); forward light scatter also correlated with recipient age (r=0.67, P< .001). Conclusions: Six months after DSEK, corneal light scatter remained greater in eyes with Fuchs endothelial dystrophy than in normal eyes and correlated with recipient age and visual acuity. Recipient age might be the best preoperative predictor of vision after DSEK.

UR - http://www.scopus.com/inward/record.url?scp=60549086170&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=60549086170&partnerID=8YFLogxK

U2 - 10.1001/archophthalmol.2008.581

DO - 10.1001/archophthalmol.2008.581

M3 - Article

C2 - 19204232

AN - SCOPUS:60549086170

VL - 127

SP - 153

EP - 160

JO - JAMA Ophthalmology

JF - JAMA Ophthalmology

SN - 2168-6165

IS - 2

ER -