MRG ile normal görünümlü beyaz ve gri cevherde yaşlanmanin etkilerinin ADC degerleri ile saptanabilirligi.

Translated title of the contribution: The effect of aging on the apparent diffusion coefficient of normal appearing white and gray matter

Yasemin M. Karadeniz Bilgili, Birsen Unal, Ayse Tuba Kendi, Ilknur Simşir, Haydar Erdal, Sinef Huvaj, Simay Kara, G. Bademci

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

PURPOSE: To test if the apparent diffusion coefficient (ADC) values reflect the ultrastructural changes of normal appearing white and gray matter with advancing age. MATERIALS AND METHODS: We selected 45 patients with normal MRI and DW imaging findings. DW and MRI imaging was performed and for each patient the average ADC on trace images of the frontal and occipital white matter and the thalamus were compared with increasing patient age. RESULTS: The average ADC value was 0.753+/-0.054 x 10-3 mm2/sec in frontal white matter, 0.673+/-0.085 x 10-3 mm2/sec in occipital white matter, and 0.763+/-0.063 x 10-3 mm2/sec in the thalamus. For white matter, ADC values increased with advancing age. Although ADC tended to increase with age, comparison of individual thalamic ADC and patient ages did not reach statistical significance. CONCLUSION: Advancing age is associated with a small but statistically significant increase of water diffusibility in human white matter. This increase may reflect mild structural changes with normal aging.

Original languageTurkish
Pages (from-to)4-7
Number of pages4
JournalTanisal ve girişimsel radyoloji : Tibbi Görüntüleme ve Girişimsel Radyoloji Dernegi yayin organi
Volume10
Issue number1
StatePublished - Jan 1 2004
Externally publishedYes

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Thalamus
White Matter
Gray Matter
Water

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

MRG ile normal görünümlü beyaz ve gri cevherde yaşlanmanin etkilerinin ADC degerleri ile saptanabilirligi. / Karadeniz Bilgili, Yasemin M.; Unal, Birsen; Tuba Kendi, Ayse; Simşir, Ilknur; Erdal, Haydar; Huvaj, Sinef; Kara, Simay; Bademci, G.

In: Tanisal ve girişimsel radyoloji : Tibbi Görüntüleme ve Girişimsel Radyoloji Dernegi yayin organi, Vol. 10, No. 1, 01.01.2004, p. 4-7.

Research output: Contribution to journalArticle

Karadeniz Bilgili, Yasemin M. ; Unal, Birsen ; Tuba Kendi, Ayse ; Simşir, Ilknur ; Erdal, Haydar ; Huvaj, Sinef ; Kara, Simay ; Bademci, G. / MRG ile normal görünümlü beyaz ve gri cevherde yaşlanmanin etkilerinin ADC degerleri ile saptanabilirligi. In: Tanisal ve girişimsel radyoloji : Tibbi Görüntüleme ve Girişimsel Radyoloji Dernegi yayin organi. 2004 ; Vol. 10, No. 1. pp. 4-7.
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abstract = "PURPOSE: To test if the apparent diffusion coefficient (ADC) values reflect the ultrastructural changes of normal appearing white and gray matter with advancing age. MATERIALS AND METHODS: We selected 45 patients with normal MRI and DW imaging findings. DW and MRI imaging was performed and for each patient the average ADC on trace images of the frontal and occipital white matter and the thalamus were compared with increasing patient age. RESULTS: The average ADC value was 0.753+/-0.054 x 10-3 mm2/sec in frontal white matter, 0.673+/-0.085 x 10-3 mm2/sec in occipital white matter, and 0.763+/-0.063 x 10-3 mm2/sec in the thalamus. For white matter, ADC values increased with advancing age. Although ADC tended to increase with age, comparison of individual thalamic ADC and patient ages did not reach statistical significance. CONCLUSION: Advancing age is associated with a small but statistically significant increase of water diffusibility in human white matter. This increase may reflect mild structural changes with normal aging.",
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AU - Karadeniz Bilgili, Yasemin M.

AU - Unal, Birsen

AU - Tuba Kendi, Ayse

AU - Simşir, Ilknur

AU - Erdal, Haydar

AU - Huvaj, Sinef

AU - Kara, Simay

AU - Bademci, G.

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N2 - PURPOSE: To test if the apparent diffusion coefficient (ADC) values reflect the ultrastructural changes of normal appearing white and gray matter with advancing age. MATERIALS AND METHODS: We selected 45 patients with normal MRI and DW imaging findings. DW and MRI imaging was performed and for each patient the average ADC on trace images of the frontal and occipital white matter and the thalamus were compared with increasing patient age. RESULTS: The average ADC value was 0.753+/-0.054 x 10-3 mm2/sec in frontal white matter, 0.673+/-0.085 x 10-3 mm2/sec in occipital white matter, and 0.763+/-0.063 x 10-3 mm2/sec in the thalamus. For white matter, ADC values increased with advancing age. Although ADC tended to increase with age, comparison of individual thalamic ADC and patient ages did not reach statistical significance. CONCLUSION: Advancing age is associated with a small but statistically significant increase of water diffusibility in human white matter. This increase may reflect mild structural changes with normal aging.

AB - PURPOSE: To test if the apparent diffusion coefficient (ADC) values reflect the ultrastructural changes of normal appearing white and gray matter with advancing age. MATERIALS AND METHODS: We selected 45 patients with normal MRI and DW imaging findings. DW and MRI imaging was performed and for each patient the average ADC on trace images of the frontal and occipital white matter and the thalamus were compared with increasing patient age. RESULTS: The average ADC value was 0.753+/-0.054 x 10-3 mm2/sec in frontal white matter, 0.673+/-0.085 x 10-3 mm2/sec in occipital white matter, and 0.763+/-0.063 x 10-3 mm2/sec in the thalamus. For white matter, ADC values increased with advancing age. Although ADC tended to increase with age, comparison of individual thalamic ADC and patient ages did not reach statistical significance. CONCLUSION: Advancing age is associated with a small but statistically significant increase of water diffusibility in human white matter. This increase may reflect mild structural changes with normal aging.

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