The dynamin family of mechanoenzymes: Pinching in new places

Mark A. McNiven, Hong Cao, Kelly R. Pitts, Yisang Yoon

Research output: Contribution to journalReview articlepeer-review

305 Scopus citations


The large GTPase dynamin is a mechanoenzyme that mediates the liberation of nascent clathrin-coated pits from the plasma membrane during endocytosis. Recently, this enzyme has been demonstrated to comprise an extensive family of related proteins that have been implicated in a large variety of vesicle trafficking events during endocytosis, secretion and even maintenance of mitochondrial form. The potential contributions by the dynamin family to these diverse but related functions are discussed. Copyright (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)115-120
Number of pages6
JournalTrends in biochemical sciences
Issue number3
StatePublished - Mar 1 2000

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology


Dive into the research topics of 'The dynamin family of mechanoenzymes: Pinching in new places'. Together they form a unique fingerprint.

Cite this