The divergent recovery of ST-segment depression and radionuclide angiographic indicators of myocardial ischemia

Pierce J. Vatterott, Peter C. Hanley, Harold T. Mankin, Raymond J. Gibbons

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

This study evaluated the recovery after exercise of both ST-segment depression on the exercise electrocardiogram (electrical evidence of ischemia) and exercise-induced abnormalities in wall motion or ejection fraction as detected by radionuclide angiography. The study group of 31 patients was selected to undergo prolonged etectrocardiographic and radionuclide imaging after exercise because they had persistent ST-segment depression >3 minutes after exercise and radionuclide angiographic evidence of ischemia at peak exercise. In 27 (87%) of the 31 patients, radionuclide evidence of ischemia recovered more quickly than the electrocardiogram. Only 15 of the 31 patients had exercise-induced radionuclide abnormalities after exercise. Compared with the 16 patients without such findings of ischemia after exercise, these 15 patients had a worse wall motion score at peak exercise (5.3 vs 3.9; p < 0.01) and a smaller increase in systolic blood pressure with exercise (p < 0.05) and after exercise (p < 0.01). Radionuclide angiographic evidence of ischemia recovers more quickly after exercise than ST-segment depression. When there is radionuclide evidence of ischemia after exercise, it is associated with more severe ischemia during exercise.

Original languageEnglish (US)
Pages (from-to)296-301
Number of pages6
JournalThe American journal of cardiology
Volume66
Issue number3
DOIs
StatePublished - Aug 1 1990

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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