The cytoplasmic body: Another structural anomaly of the Z disk

Ronald D. Macdonald; Andrew G. Engel

doi:10.1007/BF00686346

The cytoplasmic body: Another structural anomaly of the Z disk

Ronald D. Macdonald, Andrew G. Engel

Neurology

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

The "cytoplasmic body", herein described, represents another basic pathological reaction of the Z disk. It is characterized by (1) its origin in the Z disk, (2) a dense filamentous core, (3) a surrounding lighter halo, (4) randomly orientated thin and finer filaments in the halo, (5) lack of a tetragonal filamentous array regardless of the plane of the section, (6) an accompanying focal decrease of mitochrondria from the affected fibre regions, and (7) its restriction to white (type 2) fibres. These features are compared with those of other anomalies of the Z disk.

Original language	English (US)
Pages (from-to)	99-107
Number of pages	9
Journal	Acta neuropathologica
Volume	14
Issue number	2
DOIs	https://doi.org/10.1007/BF00686346
State	Published - Jun 1969

Keywords

Cytoplasmic Body
Rods of Z-Disk Origin
Z Disk
Z-Disk Streaming

ASJC Scopus subject areas

Pathology and Forensic Medicine
Clinical Neurology
Cellular and Molecular Neuroscience

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10.1007/BF00686346

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AB - The "cytoplasmic body", herein described, represents another basic pathological reaction of the Z disk. It is characterized by (1) its origin in the Z disk, (2) a dense filamentous core, (3) a surrounding lighter halo, (4) randomly orientated thin and finer filaments in the halo, (5) lack of a tetragonal filamentous array regardless of the plane of the section, (6) an accompanying focal decrease of mitochrondria from the affected fibre regions, and (7) its restriction to white (type 2) fibres. These features are compared with those of other anomalies of the Z disk.

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The cytoplasmic body: Another structural anomaly of the Z disk

Abstract

Keywords

ASJC Scopus subject areas

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