The consequences of not following a cardiac diet: Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19

Kristen B. McCullough, Wayne T. Nicholson

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This case discusses a pharmacokinetic interaction between clopidogrel and omeprazole, resulting in a decreased antiplatelet effect of clopidogrel. Clopidogrel is a cytochrome P450 2C19 substrate and omeprazole is a 2C19 inhibitor.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Pages675-679
Number of pages5
ISBN (Print)9781461474951, 9781461474944
DOIs
StatePublished - Sep 15 2015

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clopidogrel
Omeprazole
Diet
Cytochrome P-450 Enzyme System
Pharmacokinetics
Cytochrome P-450 CYP2C19

ASJC Scopus subject areas

  • Medicine(all)

Cite this

McCullough, K. B., & Nicholson, W. T. (2015). The consequences of not following a cardiac diet: Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 675-679). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_150

The consequences of not following a cardiac diet : Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19. / McCullough, Kristen B.; Nicholson, Wayne T.

A Case Approach to Perioperative Drug-Drug Interactions. Springer New York, 2015. p. 675-679.

Research output: Chapter in Book/Report/Conference proceedingChapter

McCullough, KB & Nicholson, WT 2015, The consequences of not following a cardiac diet: Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19. in A Case Approach to Perioperative Drug-Drug Interactions. Springer New York, pp. 675-679. https://doi.org/10.1007/978-1-4614-7495-1_150
McCullough KB, Nicholson WT. The consequences of not following a cardiac diet: Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19. In A Case Approach to Perioperative Drug-Drug Interactions. Springer New York. 2015. p. 675-679 https://doi.org/10.1007/978-1-4614-7495-1_150
McCullough, Kristen B. ; Nicholson, Wayne T. / The consequences of not following a cardiac diet : Fatal forty DDI: Clopidogrel, omeprazole, CYP2C19. A Case Approach to Perioperative Drug-Drug Interactions. Springer New York, 2015. pp. 675-679
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