The clinical significance of quality of life assessments in oncology: A summary for clinicians

Jeff A. Sloan, Marlene H. Frost, Rick Berzon, Amylou Dueck, Gordon Guyatt, Carol Moinpour, Mirjam Sprangers, Carol Ferrans, David Cella, Neil Aaronson, Ivan Barofsky, Amy Bonomi, Monika Bullinger, Joseph Cappelleri, Diane Fairclough, Larry Gorkin, Ron Hays, Patrick Marquis, Tim Moynihan, Geoff NormanDavid Osoba, Donald Patrick, Dennis Revicki, Theresa Rummans, Charles Scott, Tara Symonds, Claudette Varricchio, Gilbert Wong, Albert Wu, Kathleen Wyrwich

Research output: Contribution to journalReview article

115 Scopus citations

Abstract

Background: A series of six manuscripts with an introduction appeared in the Mayo Clinic Proceedings, based upon the collective effort of 30 individuals with an interest and expertise in assessing the clinical significance of quality of life (QOL) assessments. The series of manuscripts described the state of the science of QOL assessments in oncology clinical research and practice and included extensive literature and theoretical justification for the continued inclusion of QOL in oncology clinical research and practice. Objectives: The purpose of this paper is to produce a summary of these articles and to supplement these works with additional information that was gleaned from subsequent meetings and discussions of this material. The primary aim of this paper is to present a cogent and concise description for clinicians to facilitate the incorporation of QOL assessments into oncology clinical research and practice. The theoretical discussion is supplemented with an example of how the various ideas can be operationalized in an oncology clinical trial.

Original languageEnglish (US)
Pages (from-to)988-998
Number of pages11
JournalSupportive Care in Cancer
Volume14
Issue number10
DOIs
StatePublished - Oct 1 2006

Keywords

  • Cancer
  • Oncology
  • QOL

ASJC Scopus subject areas

  • Oncology

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    Sloan, J. A., Frost, M. H., Berzon, R., Dueck, A., Guyatt, G., Moinpour, C., Sprangers, M., Ferrans, C., Cella, D., Aaronson, N., Barofsky, I., Bonomi, A., Bullinger, M., Cappelleri, J., Fairclough, D., Gorkin, L., Hays, R., Marquis, P., Moynihan, T., ... Wyrwich, K. (2006). The clinical significance of quality of life assessments in oncology: A summary for clinicians. Supportive Care in Cancer, 14(10), 988-998. https://doi.org/10.1007/s00520-006-0085-y