TY - JOUR
T1 - The cancer anorexia/weight loss syndrome
T2 - Therapeutic challenges
AU - Giordano, Karin F.
AU - Jatoi, Aminah
PY - 2005/7
Y1 - 2005/7
N2 - The cancer anorexia/weight loss syndrome is characterized by loss of weight, loss of appetite, overall decline in quality of life, and shortened survival in patients with advanced incurable cancer. It is highly prevalent. To date, treatment options that have been firmly established with good scientific evidence are limited to progestational agents and corticosteroids, both of which have been demonstrated to improve appetite but have otherwise failed to have a favorable impact on some of the other aspects of this syndrome. As the mechanisms behind this syndrome are further elucidated, more effective therapeutic strategies will likely emerge.
AB - The cancer anorexia/weight loss syndrome is characterized by loss of weight, loss of appetite, overall decline in quality of life, and shortened survival in patients with advanced incurable cancer. It is highly prevalent. To date, treatment options that have been firmly established with good scientific evidence are limited to progestational agents and corticosteroids, both of which have been demonstrated to improve appetite but have otherwise failed to have a favorable impact on some of the other aspects of this syndrome. As the mechanisms behind this syndrome are further elucidated, more effective therapeutic strategies will likely emerge.
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U2 - 10.1007/s11912-005-0050-9
DO - 10.1007/s11912-005-0050-9
M3 - Review article
C2 - 15946586
AN - SCOPUS:23344454966
SN - 1523-3790
VL - 7
SP - 271
EP - 276
JO - Current oncology reports
JF - Current oncology reports
IS - 4
ER -