@inproceedings{c142da637b7446c3bdd217d38aae9b2a,
title = "The brain-machine interface: Nanotechniques for improving brain electrochemical monitoring and modulating",
abstract = "Present neuromodulation (e.g. deep brain stimulation-DBS) has inefficient charge transfer from electrode to brain tissue, and lacks both neurotransmitter monitoring and feedback-guided stimulation. Six 50 × 20 μm carbon nano-fiber (CNF) {"}pads{"} on an electrode 1/10 the diameter of a DBS electrode can either stimulate or record electrical activity or monitor a neurotransmitter level. Novel fast-scan cyclic voltammetry (FSCV) methods allow continuous recording of two neurotransmitters. Conducting polymers on CNF electrodes reduce impedance and increase capacitance orders of magnitude above platinum electrodes. CNF electrodes detect concentration changes in either of two neurotransmitters, e.g. dopamine and serotonin, in ascorbic acid (ubiquitous in brain), unlike standard FSCV electrodes. A Bluetooth wireless system allows remote monitoring of both electrical and chemical brain activity with precise spatial-temporal resolution, increasing understanding of brain function - both normal and disordered.",
keywords = "Brain-machine interface, Deep brain stimulation, Nanoelectrodes, Neuromodulation, Neurotransmitters",
author = "R. Andrews and K. Bennet and Chang, {S. Y.} and J. Koehne and K. Lee and M. Marsh and M. Meyyappan and E. Rand",
year = "2016",
language = "English (US)",
series = "Advanced Materials - TechConnect Briefs 2016",
publisher = "TechConnect",
pages = "61--64",
editor = "Fiona Case and Matthew Laudon and Fiona Case and Bart Romanowicz and Bart Romanowicz",
booktitle = "Advanced Materials - TechConnect Briefs 2016",
note = "10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 19th Annual Nanotech Conference and Expo, and the 2016 National SBIR/STTR Conference ; Conference date: 22-05-2016 Through 25-05-2016",
}