The biological basis of troponin in heart disease: Possible uses for troponin fragmentology

Vlad C. Vasile, Allan S. Jaffe

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

This article describes the molecular biology of troponin in heart disease. Prospective uses for this biomarker are mentioned, with a particular emphasis on cardiac troponin fragments that could be associated with distinct clinical entities. The article explores the topic of specific cardiac troponin fragments resulting from modification or degradation, linked with different pathological processes, as indications of novel potential uses for this biomarker in heart disease. In addition, it addresses some implications that could have an impact on several circumstances that confront physicians within clinical practice.

Original languageEnglish (US)
Pages (from-to)5-8
Number of pages4
JournalHeart and Metabolism
Issue number43
StatePublished - Sep 28 2009

Keywords

  • Dephosphorylation
  • Phosphorylation
  • Troponin fragments

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

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