The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins

Matthias A. Hediger; Michael F. Romero; Ji Bin Peng; Andreas Rolfs; Hitomi Takanaga; Elspeth A. Bruford

doi:10.1007/s00424-003-1192-y

The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins

Matthias A. Hediger, Michael F. Romero, Ji Bin Peng, Andreas Rolfs, Hitomi Takanaga, Elspeth A. Bruford

Physiology & Biomedical Engineering

Research output: Contribution to journal › Review article › peer-review

650 Scopus citations

Abstract

The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/. Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/ slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.

Original language	English (US)
Pages (from-to)	465-468
Number of pages	4
Journal	Pflugers Archiv European Journal of Physiology
Volume	447
Issue number	5
DOIs	https://doi.org/10.1007/s00424-003-1192-y
State	Published - Feb 2004

Keywords

ABC transporter
Carrier
Channel
Cotransporter
Coupled transport
Exchanger
Ion transport
Nomenclature
Pump
SLC
Solute transport
Transport protein
Transporter
Transporter gene
Uniporter

ASJC Scopus subject areas

Physiology
Clinical Biochemistry
Physiology (medical)

Access to Document

10.1007/s00424-003-1192-y

Cite this

@article{09e002f3bac643d1bc4f55d9744dba4c,

title = "The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins",

abstract = "The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/. Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/ slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.",

keywords = "ABC transporter, Carrier, Channel, Cotransporter, Coupled transport, Exchanger, Ion transport, Nomenclature, Pump, SLC, Solute transport, Transport protein, Transporter, Transporter gene, Uniporter",

author = "Hediger, {Matthias A.} and Romero, {Michael F.} and Peng, {Ji Bin} and Andreas Rolfs and Hitomi Takanaga and Bruford, {Elspeth A.}",

year = "2004",

month = feb,

doi = "10.1007/s00424-003-1192-y",

language = "English (US)",

volume = "447",

pages = "465--468",

journal = "Pflugers Archiv European Journal of Physiology",

issn = "0031-6768",

publisher = "Springer Verlag",

number = "5",

}

TY - JOUR

T1 - The ABCs of solute carriers

T2 - Physiological, pathological and therapeutic implications of human membrane transport proteins

AU - Hediger, Matthias A.

AU - Romero, Michael F.

AU - Peng, Ji Bin

AU - Rolfs, Andreas

AU - Takanaga, Hitomi

AU - Bruford, Elspeth A.

PY - 2004/2

Y1 - 2004/2

N2 - The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/. Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/ slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.

AB - The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/. Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/ slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.

KW - ABC transporter

KW - Carrier

KW - Channel

KW - Cotransporter

KW - Coupled transport

KW - Exchanger

KW - Ion transport

KW - Nomenclature

KW - Pump

KW - SLC

KW - Solute transport

KW - Transport protein

KW - Transporter

KW - Transporter gene

KW - Uniporter

UR - http://www.scopus.com/inward/record.url?scp=1242340323&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=1242340323&partnerID=8YFLogxK

U2 - 10.1007/s00424-003-1192-y

DO - 10.1007/s00424-003-1192-y

M3 - Review article

C2 - 14624363

AN - SCOPUS:1242340323

SN - 0031-6768

VL - 447

SP - 465

EP - 468

JO - Pflugers Archiv European Journal of Physiology

JF - Pflugers Archiv European Journal of Physiology

IS - 5

ER -

The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this