The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins

Matthias A. Hediger; Michael F. Romero; Ji Bin Peng; Andreas Rolfs; Hitomi Takanaga; Elspeth A. Bruford

doi:10.1007/s00424-003-1192-y

The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins

Matthias A. Hediger, Michael F. Romero, Ji Bin Peng, Andreas Rolfs, Hitomi Takanaga, Elspeth A. Bruford

Physiology & Biomedical Engineering

Research output: Contribution to journal › Review article › peer-review

650 Scopus citations

Abstract

The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/. Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/ slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.

Original language	English (US)
Pages (from-to)	465-468
Number of pages	4
Journal	Pflugers Archiv European Journal of Physiology
Volume	447
Issue number	5
DOIs	https://doi.org/10.1007/s00424-003-1192-y
State	Published - Feb 1 2004

Keywords

ABC transporter
Carrier
Channel
Cotransporter
Coupled transport
Exchanger
Ion transport
Nomenclature
Pump
SLC
Solute transport
Transport protein
Transporter
Transporter gene
Uniporter

ASJC Scopus subject areas

Physiology
Clinical Biochemistry
Physiology (medical)

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10.1007/s00424-003-1192-y

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abstract = "The Human Genome Organisation (HUGO) Nomenclature Committee Database provides a list of transporter families of the solute carrier (SLC) gene series (see http://www.gene.ucl.ac.uk/nomenclature/. Currently, it includes 43 families and 298 transporter genes. This special issue features mini-reviews on each of these SLC families written by the experts in each field. A WEB site has been established (http://www.pharmaconference.org/ slctable.asp) that gives the latest updates for the SLC families and their members as well as relevant links to gene databases and reviews in the literature. A list of all currently known SLC families, a discussion of additional SLC families and family members as well as a brief summary of non-SLC transporter genes is included in this introduction.",

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AU - Rolfs, Andreas

AU - Takanaga, Hitomi

AU - Bruford, Elspeth A.

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The ABCs of solute carriers: Physiological, pathological and therapeutic implications of human membrane transport proteins

Abstract

Keywords

ASJC Scopus subject areas

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