The 5q- syndrome: A scientific and clinical update

Ayalew Tefferi, Paul Mathew, Pierre Noël

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

The 5q- syndrome is a subset of the myelodysplastic syndromes characterized by hypolob-ulated micromegakaryocytic hyperplasia and an interstitial deletion of the long arm of chromosome 5. In this concise review, we discuss the current understanding in regard to the genetic basis of the disorder and provide an updated clinical report on 43 patients with the disease who were seen at our institution.

Original languageEnglish (US)
Pages (from-to)375-378
Number of pages4
JournalLeukemia and Lymphoma
Volume14
Issue number5-6
DOIs
StatePublished - 1994

Fingerprint

Chromosomes, Human, Pair 5
Inborn Genetic Diseases
Myelodysplastic Syndromes
Hyperplasia
Chromosome 5q Deletion Syndrome

Keywords

  • 5q-
  • Clinical course
  • Molecular genetics
  • Myelodysplastic syndrome

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

Cite this

The 5q- syndrome : A scientific and clinical update. / Tefferi, Ayalew; Mathew, Paul; Noël, Pierre.

In: Leukemia and Lymphoma, Vol. 14, No. 5-6, 1994, p. 375-378.

Research output: Contribution to journalArticle

Tefferi, Ayalew ; Mathew, Paul ; Noël, Pierre. / The 5q- syndrome : A scientific and clinical update. In: Leukemia and Lymphoma. 1994 ; Vol. 14, No. 5-6. pp. 375-378.
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