Thalamic stimulation for the treatment of midline tremors in essential tremor patients

A. A. Obwegeser; R. J. Uitti; M. F. Turk; A. J. Strongosky; Robert E. Wharen

doi:10.1212/WNL.54.12.2342

Thalamic stimulation for the treatment of midline tremors in essential tremor patients

A. A. Obwegeser, R. J. Uitti, M. F. Turk, A. J. Strongosky, Robert E. Wharen

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Abstract

The authors prospectively collected unblinded data from 27 consecutive patients following thalamic stimulation. A significant reduction of midline tremor was achieved after unilateral surgery, but a staged contralateral surgery had an additional effect. A subgroup analysis showed significant beneficial effects for head, voice, tongue, and face tremor. The most frequent reversible side effects were disequilibrium, dysarthria, and paresthesias. We observed more pulse generator adjustments for speech problems in the bilaterally implanted group.

Original language	English (US)
Pages (from-to)	2342-2344
Number of pages	3
Journal	Neurology
Volume	54
Issue number	12
DOIs	https://doi.org/10.1212/WNL.54.12.2342
State	Published - Jun 27 2000

Keywords

Essential tremor
Stimulation
Thalamic nuclei

ASJC Scopus subject areas

Clinical Neurology

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10.1212/WNL.54.12.2342

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title = "Thalamic stimulation for the treatment of midline tremors in essential tremor patients",

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keywords = "Essential tremor, Stimulation, Thalamic nuclei",

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AU - Obwegeser, A. A.

AU - Uitti, R. J.

AU - Turk, M. F.

AU - Strongosky, A. J.

AU - Wharen, Robert E.

PY - 2000/6/27

Y1 - 2000/6/27

N2 - The authors prospectively collected unblinded data from 27 consecutive patients following thalamic stimulation. A significant reduction of midline tremor was achieved after unilateral surgery, but a staged contralateral surgery had an additional effect. A subgroup analysis showed significant beneficial effects for head, voice, tongue, and face tremor. The most frequent reversible side effects were disequilibrium, dysarthria, and paresthesias. We observed more pulse generator adjustments for speech problems in the bilaterally implanted group.

AB - The authors prospectively collected unblinded data from 27 consecutive patients following thalamic stimulation. A significant reduction of midline tremor was achieved after unilateral surgery, but a staged contralateral surgery had an additional effect. A subgroup analysis showed significant beneficial effects for head, voice, tongue, and face tremor. The most frequent reversible side effects were disequilibrium, dysarthria, and paresthesias. We observed more pulse generator adjustments for speech problems in the bilaterally implanted group.

KW - Essential tremor

KW - Stimulation

KW - Thalamic nuclei

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Thalamic stimulation for the treatment of midline tremors in essential tremor patients

Abstract

Keywords

ASJC Scopus subject areas

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