TGF-β inducible early gene 1 regulates osteoclast differentiation and survival by mediating the NFATc1, AKT, and MEK/ERK signaling pathways

Medicine & Life Sciences

• MAP Kinase Signaling System 79%
• Osteoclasts 74%
• Survival 40%
• Genes 29%
• Apoptosis 6%
• Cortical Bone 5%
• Mitogen-Activated Protein Kinase Kinases 5%
• Osteoblasts 4%
• Small Interfering RNA 4%
• Cell Differentiation 4%
• Thigh 4%
• Phosphotransferases 3%
• Transcription Factors 3%
• Phosphorylation 3%
• Phenotype 3%
• Bone and Bones 3%
• In Vitro Techniques 2%

Agriculture & Biology

• osteoclasts 100%
• mitogen-activated protein kinase 78%
• genes 24%
• apoptosis 9%
• bones 8%
• osteoblasts 6%
• small interfering RNA 5%
• thighs 5%
• phosphorylation 4%
• phosphotransferases (kinases) 4%
• spatial distribution 4%
• transcription factors 4%
• phenotype 3%
• cells 3%
• mice 2%
• dosage 2%

Chemical Compounds

• Silencing RNA 93%
• Dose 55%
• Volume 41%