Texture analysis of MR images of minocycline treated MS patients

Yunyan Zhang, Hongmei Zhu, Ricardo Ferrari, Xingchang Wei, Michael Eliasziw, Luanne M. Metz, Joseph Ross Mitchell

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Texture analysis was applied to 3T brain MR images of 5 relapsing remitting MS patients before and after minocycline treatment. Texture features were used to quantify pathological changes that may be undetectable by conventional MR techniques. Active, inactive lesions and NAWM were chosen from MR images of MS patients one month before and six months after treatment. Texture features changed in all of the selected ROIs. Texture change in active lesions was greater than that in inactive lesions and NAWM. There was close relationship between texture changes in active lesions and NAWM. This preliminary work suggests that it may be possible to predict therapeutic response of MS patients using MRI texture analysis.

Original languageEnglish (US)
Pages (from-to)786-793
Number of pages8
JournalLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume2878
StatePublished - 2003
Externally publishedYes

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Texture Analysis
Minocycline
Texture Feature
Texture
Textures
Quantify
Predict
Therapeutics
Brain
Magnetic resonance imaging
Relationships

ASJC Scopus subject areas

  • Computer Science(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Theoretical Computer Science
  • Computer Science (miscellaneous)
  • Engineering(all)

Cite this

Texture analysis of MR images of minocycline treated MS patients. / Zhang, Yunyan; Zhu, Hongmei; Ferrari, Ricardo; Wei, Xingchang; Eliasziw, Michael; Metz, Luanne M.; Mitchell, Joseph Ross.

In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Vol. 2878, 2003, p. 786-793.

Research output: Contribution to journalArticle

Zhang, Yunyan ; Zhu, Hongmei ; Ferrari, Ricardo ; Wei, Xingchang ; Eliasziw, Michael ; Metz, Luanne M. ; Mitchell, Joseph Ross. / Texture analysis of MR images of minocycline treated MS patients. In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 2003 ; Vol. 2878. pp. 786-793.
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