Tetraploidy acute promyelocytic leuemia with double t(15;17)/PML-RARA, a case report with review of literature

Samir M. Dalia, Pedro Horna, Ling Zhang

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Acute promyelocytic leukemia (APL) with tetraploidy chromosome harboring t(15;17)(q23;a21) is extremely rare. To date, there are 14 such cases reports that describe this entity, mostly found in Eastern hemisphere. Herein we described a 51-year-old man with a diagnosis of tetraploid acute promyelocytic leukemia with double (15;17) translocations and compare the prototypically clinicopathologic, genetic and molecular findings with those reported in the literature.

Original languageEnglish (US)
Pages (from-to)5363-5368
Number of pages6
JournalInternational Journal of Clinical and Experimental Pathology
Volume7
Issue number8
StatePublished - Jan 1 2014

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Keywords

  • Acute promyelocytic leukemia
  • All trans-retinoic acid (ATRA)
  • Leukemia
  • PML-RARA
  • Tetraploid

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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