Abstract
Acute promyelocytic leukemia (APL) with tetraploidy chromosome harboring t(15;17)(q23;a21) is extremely rare. To date, there are 14 such cases reports that describe this entity, mostly found in Eastern hemisphere. Herein we described a 51-year-old man with a diagnosis of tetraploid acute promyelocytic leukemia with double (15;17) translocations and compare the prototypically clinicopathologic, genetic and molecular findings with those reported in the literature.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 5363-5368 |
| Number of pages | 6 |
| Journal | International Journal of Clinical and Experimental Pathology |
| Volume | 7 |
| Issue number | 8 |
| State | Published - Jan 1 2014 |
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Keywords
- Acute promyelocytic leukemia
- All trans-retinoic acid (ATRA)
- Leukemia
- PML-RARA
- Tetraploid
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology
Cite this
Dalia, S. M., Horna, P., & Zhang, L. (2014). Tetraploidy acute promyelocytic leuemia with double t(15;17)/PML-RARA, a case report with review of literature. International Journal of Clinical and Experimental Pathology, 7(8), 5363-5368.