Abstract
Acute promyelocytic leukemia (APL) with tetraploidy chromosome harboring t(15;17)(q23;a21) is extremely rare. To date, there are 14 such cases reports that describe this entity, mostly found in Eastern hemisphere. Herein we described a 51-year-old man with a diagnosis of tetraploid acute promyelocytic leukemia with double (15;17) translocations and compare the prototypically clinicopathologic, genetic and molecular findings with those reported in the literature.
Original language | English (US) |
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Pages (from-to) | 5363-5368 |
Number of pages | 6 |
Journal | International Journal of Clinical and Experimental Pathology |
Volume | 7 |
Issue number | 8 |
State | Published - Jan 1 2014 |
Keywords
- Acute promyelocytic leukemia
- All trans-retinoic acid (ATRA)
- Leukemia
- PML-RARA
- Tetraploid
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology