Teratocarcinoma transplantation antigens are encoded in the H-2 region

Lawrence L. Johnson, Linda J. Clipson, William F. Dove, John Feilbach, L. James Maher, Alexandra Shedlovsk

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

Evidence is presented for the existence of teratocarcinoma transplantation antigens (Gt) encoded within the H-2 complex and present also on adult tissues. It has not been possible to separate these Gt loci from H-2 by recombination, and Gt factors map to each end of the H-2 complex. Previous reports indicating separation of all Gt loci from H-2 are reinterpreted. One class of such apparent recombinants has been shown to result from the outgrowth of tumor variants in mice of resistant genotype.

Original languageEnglish (US)
Pages (from-to)137-145
Number of pages9
JournalImmunogenetics
Volume18
Issue number2
DOIs
StatePublished - Aug 1983

ASJC Scopus subject areas

  • Immunology
  • Genetics

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