Abstract
Evidence is presented for the existence of teratocarcinoma transplantation antigens (Gt) encoded within the H-2 complex and present also on adult tissues. It has not been possible to separate these Gt loci from H-2 by recombination, and Gt factors map to each end of the H-2 complex. Previous reports indicating separation of all Gt loci from H-2 are reinterpreted. One class of such apparent recombinants has been shown to result from the outgrowth of tumor variants in mice of resistant genotype.
Original language | English (US) |
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Pages (from-to) | 137-145 |
Number of pages | 9 |
Journal | Immunogenetics |
Volume | 18 |
Issue number | 2 |
DOIs | |
State | Published - Aug 1983 |
ASJC Scopus subject areas
- Immunology
- Genetics