Temporary encapsulation of rat marrow osteoblasts in gelatin microspheres for bone tissue engineering

Richard G. Payne, Alan W. Yasko, Michael J. Yaszemski, Antonios G. Mikos

Research output: Contribution to journalConference article

4 Scopus citations

Abstract

Primary marrow stromal osteoblasts were temporarily encapsulated in gelatin microspheres. They were cultured for 28 days and compared to nonencapsulated control cells in assays for cell number, proliferation, and osteoblastic phenotypic expression. Results show that in all assays, encapsulated cells had values similar to those of control cells throughout the 28 day study. This study indicates that this encapsulation method is a promising initial step in allowing cells to be incorporated into an injectable, biodegradable polymeric composite for bone tissue engineering.

Original languageEnglish (US)
Pages (from-to)LL1.7.1-LL1.7.5
JournalMaterials Research Society Symposium - Proceedings
Volume662
StatePublished - Dec 1 2001
EventBiomaterials for Drug Delivery and Tissue Engineering - Boston, MA, United States
Duration: Nov 27 2000Nov 29 2000

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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