Temporary encapsulation of rat marrow osteoblasts in gelatin microspheres for bone tissue engineering

Richard G. Payne, Alan W. Yasko, Michael J Yaszemski, Antonios G. Mikos

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Primary marrow stromal osteoblasts were temporarily encapsulated in gelatin microspheres. They were cultured for 28 days and compared to nonencapsulated control cells in assays for cell number, proliferation, and osteoblastic phenotypic expression. Results show that in all assays, encapsulated cells had values similar to those of control cells throughout the 28 day study. This study indicates that this encapsulation method is a promising initial step in allowing cells to be incorporated into an injectable, biodegradable polymeric composite for bone tissue engineering.

Original languageEnglish (US)
Title of host publicationMaterials Research Society Symposium - Proceedings
EditorsS Mallapragada, M Tracy, B Narasimhan, E Mathiowitz, R Korsmeyer
Volume662
StatePublished - 2001
Externally publishedYes
EventBiomaterials for Drug Delivery and Tissue Engineering - Boston, MA, United States
Duration: Nov 27 2000Nov 29 2000

Other

OtherBiomaterials for Drug Delivery and Tissue Engineering
CountryUnited States
CityBoston, MA
Period11/27/0011/29/00

Fingerprint

Osteoblasts
Gelatin
Microspheres
Encapsulation
Tissue engineering
Rats
Assays
Bone
Composite materials

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

Payne, R. G., Yasko, A. W., Yaszemski, M. J., & Mikos, A. G. (2001). Temporary encapsulation of rat marrow osteoblasts in gelatin microspheres for bone tissue engineering. In S. Mallapragada, M. Tracy, B. Narasimhan, E. Mathiowitz, & R. Korsmeyer (Eds.), Materials Research Society Symposium - Proceedings (Vol. 662)

Temporary encapsulation of rat marrow osteoblasts in gelatin microspheres for bone tissue engineering. / Payne, Richard G.; Yasko, Alan W.; Yaszemski, Michael J; Mikos, Antonios G.

Materials Research Society Symposium - Proceedings. ed. / S Mallapragada; M Tracy; B Narasimhan; E Mathiowitz; R Korsmeyer. Vol. 662 2001.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Payne, RG, Yasko, AW, Yaszemski, MJ & Mikos, AG 2001, Temporary encapsulation of rat marrow osteoblasts in gelatin microspheres for bone tissue engineering. in S Mallapragada, M Tracy, B Narasimhan, E Mathiowitz & R Korsmeyer (eds), Materials Research Society Symposium - Proceedings. vol. 662, Biomaterials for Drug Delivery and Tissue Engineering, Boston, MA, United States, 11/27/00.
Payne RG, Yasko AW, Yaszemski MJ, Mikos AG. Temporary encapsulation of rat marrow osteoblasts in gelatin microspheres for bone tissue engineering. In Mallapragada S, Tracy M, Narasimhan B, Mathiowitz E, Korsmeyer R, editors, Materials Research Society Symposium - Proceedings. Vol. 662. 2001
Payne, Richard G. ; Yasko, Alan W. ; Yaszemski, Michael J ; Mikos, Antonios G. / Temporary encapsulation of rat marrow osteoblasts in gelatin microspheres for bone tissue engineering. Materials Research Society Symposium - Proceedings. editor / S Mallapragada ; M Tracy ; B Narasimhan ; E Mathiowitz ; R Korsmeyer. Vol. 662 2001.
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