Temporal trends of ventilator-associated pneumonia incidence and the effect of implementing health-care bundles in a suburban community

Shifang Ding, Oguz Kilickaya, Serkan Senkal, Ognjen Gajic, Rolf D. Hubmayr, Guangxi Li

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: Recent changes in critical care delivery, including the widespread implementation of health-care bundles, were aimed at reducing complications of critical illness, in particular ventilator-associated pneumonia (VAP), but no population-based study evaluated its effectiveness. Methods: Using a previously validated electronic medical record database, we identified adult (≥ 18 years old) critically ill patients from Olmsted County, Minnesota, requiring mechanical ventilation for ≥ 48 h from January 2003 to December 2009. Trained intensivists identified cases of VAP according to different established clinical definitions. The incidence and outcome of VAP was compared before and after implementation of the so-called "VAP bundle." Results: The median age, severity of illness, proportion of surgical patients, and patients with neurologic disease increased over time (P<.05 for trend in all). Regardless of the definition used, the VAP rate remained similar throughout the study period and did not change with the introduction of the VAP bundle. According to previous Centers for Disease Control and Prevention criteria, the yearly estimates of the VAP incidence ranged between 7.1 and 10.4 cases per 1,000 ventilatordays, with an age-adjusted incidence of 3.1 vs 5.6 per 100,000 population (P =.54 for trends). Standardized hospital mortality ratio of patients at high risk to develop VAP significantly decreased from 1.7 (95% CI, 0.8-3.0) to 0.7 (95% CI, 0.3-1.4; P =.0003 for trend). Conclusions: The incidence of VAP was unaffected by the implementation of the VAP bundle. Secular changes in hospital mortality are unlikely to be attributed to the VAP bundle per se.

Original languageEnglish (US)
Pages (from-to)1461-1468
Number of pages8
JournalChest
Volume144
Issue number5
DOIs
StatePublished - Nov 2013

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Patient Care Bundles
Ventilator-Associated Pneumonia
Delivery of Health Care
Incidence
Hospital Mortality
Critical Illness
Electronic Health Records
Critical Care
Centers for Disease Control and Prevention (U.S.)
Nervous System Diseases
Artificial Respiration
Population

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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Temporal trends of ventilator-associated pneumonia incidence and the effect of implementing health-care bundles in a suburban community. / Ding, Shifang; Kilickaya, Oguz; Senkal, Serkan; Gajic, Ognjen; Hubmayr, Rolf D.; Li, Guangxi.

In: Chest, Vol. 144, No. 5, 11.2013, p. 1461-1468.

Research output: Contribution to journalArticle

Ding, Shifang ; Kilickaya, Oguz ; Senkal, Serkan ; Gajic, Ognjen ; Hubmayr, Rolf D. ; Li, Guangxi. / Temporal trends of ventilator-associated pneumonia incidence and the effect of implementing health-care bundles in a suburban community. In: Chest. 2013 ; Vol. 144, No. 5. pp. 1461-1468.
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