Temporal reflected logistic regression for probabilistic heart failure survival score prediction

Mingjie Qian, Jyotishman Pathak, Naveen Luke Pereira, Chengxiang Zhai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Heart failure (HF) has a highly variable annual mortality rate and there is an urgent need of determining patient prognosis to enable informed decision-making about heart failure treatment strategies. Existing survival risk prediction models either require features that limit their applicability or pose difficulties for parameter estimation as physicians have to use a limited set of variables with known hazard ratios published in literature. We propose a new model to predict the probabilistic survival score after HF diagnosis based on all clinical variables derived from the electronic health record (EHR). We formalize the parameter estimation problem by using the maximum likelihood estimation (MLE) principle and devise an effective and efficient algorithm to solve the optimization problem. Experimental results using EHR data of 234 HF patients validate the superiority of this new model in predicting prognosis over the currently used Seattle Heart Failure Model.

Original languageEnglish (US)
Title of host publicationProceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages410-416
Number of pages7
Volume2017-January
ISBN (Electronic)9781509030491
DOIs
StatePublished - Dec 15 2017
Event2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017 - Kansas City, United States
Duration: Nov 13 2017Nov 16 2017

Other

Other2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017
CountryUnited States
CityKansas City
Period11/13/1711/16/17

Keywords

  • Electronic Health Records
  • Heart Failure (HF) Survival Score Prediction
  • Logistic Regression
  • Temporal Models

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics

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  • Cite this

    Qian, M., Pathak, J., Pereira, N. L., & Zhai, C. (2017). Temporal reflected logistic regression for probabilistic heart failure survival score prediction. In Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017 (Vol. 2017-January, pp. 410-416). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BIBM.2017.8217684