Temporal lobectomy outcome in older versus younger adults

Joseph I. Sirven; Barbara L. Malamut; Michael J. O'Connor; Michael R. Sperling

doi:10.1212/wnl.54.11.2166

Temporal lobectomy outcome in older versus younger adults

Joseph I. Sirven, Barbara L. Malamut, Michael J. O'Connor, Michael R. Sperling

Neurology

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64 Scopus citations

Abstract

A total of 340 patients age 50 years and older were compared with 30 patients younger than 50 years, all of whom had anterior temporal lobectomy for refractory epilepsy. Seizure outcome, neuropsychological test scores, and change in driving status were analyzed. Age and duration of epilepsy were related independently to outcome, but laterality of interictal sharp waves (an early epilepsy risk factor) and presence of tumor were not. Sixteen patients (52%) in the older group and 257 patients (75.6%) in the younger group (p < 0.008) were seizure free. Postoperative neuropsychological outcome and driving status were similar in older and younger patients.

Original language	English (US)
Pages (from-to)	2166-2169
Number of pages	4
Journal	Neurology
Volume	54
Issue number	11
DOIs	https://doi.org/10.1212/wnl.54.11.2166
State	Published - Jun 13 2000

Keywords

Elderly
Epilepsy
Seizures
Temporal lobectomy

ASJC Scopus subject areas

Clinical Neurology

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10.1212/wnl.54.11.2166

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AU - Sirven, Joseph I.

AU - Malamut, Barbara L.

AU - O'Connor, Michael J.

AU - Sperling, Michael R.

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AB - A total of 340 patients age 50 years and older were compared with 30 patients younger than 50 years, all of whom had anterior temporal lobectomy for refractory epilepsy. Seizure outcome, neuropsychological test scores, and change in driving status were analyzed. Age and duration of epilepsy were related independently to outcome, but laterality of interictal sharp waves (an early epilepsy risk factor) and presence of tumor were not. Sixteen patients (52%) in the older group and 257 patients (75.6%) in the younger group (p < 0.008) were seizure free. Postoperative neuropsychological outcome and driving status were similar in older and younger patients.

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KW - Epilepsy

KW - Seizures

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Temporal lobectomy outcome in older versus younger adults

Abstract

Keywords

ASJC Scopus subject areas

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