Abstract
It is well known and has been clearly demonstrated that temperature plays a significant role in cerebral physiology and physiopathology, particularly in the setting of cardiac surgery with cardiopulmonary bypass (CPB). The human central nervous system (CNS) receives about 15% of the resting cardiac output and consumes about 20% of the oxygen required by the body at rest. The brain, which accounts for 2% of the total body weight, has an oxygen consumption of about 3.5 mL-1·100 g-1·min-1. This high metabolic rate mandates a high blood flow; therefore, cerebral blood flow (CBF) (Fig. 13.1) is of paramount importance and is normally under metabolic, neural, myogenic, and chemical control.1
Original language | English (US) |
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Title of host publication | Brain Protection in Cardiac Surgery |
Publisher | Springer London |
Pages | 141-157 |
Number of pages | 17 |
ISBN (Print) | 9781849962926 |
DOIs | |
State | Published - 2011 |
ASJC Scopus subject areas
- General Medicine