Abstract
It is well known and has been clearly demonstrated that temperature plays a significant role in cerebral physiology and physiopathology, particularly in the setting of cardiac surgery with cardiopulmonary bypass (CPB). The human central nervous system (CNS) receives about 15% of the resting cardiac output and consumes about 20% of the oxygen required by the body at rest. The brain, which accounts for 2% of the total body weight, has an oxygen consumption of about 3.5 mL-1·100 g-1·min-1. This high metabolic rate mandates a high blood flow; therefore, cerebral blood flow (CBF) (Fig. 13.1) is of paramount importance and is normally under metabolic, neural, myogenic, and chemical control.1
| Original language | English (US) |
|---|---|
| Title of host publication | Brain Protection in Cardiac Surgery |
| Publisher | Springer London |
| Pages | 141-157 |
| Number of pages | 17 |
| ISBN (Print) | 9781849962926 |
| DOIs | |
| State | Published - 2011 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Temperature and brain protection in cardiac surgery. / Djaiani, George; Ramakrishna, Harish; Grigore, Alina M.
Brain Protection in Cardiac Surgery. Springer London, 2011. p. 141-157.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Temperature and brain protection in cardiac surgery
AU - Djaiani, George
AU - Ramakrishna, Harish
AU - Grigore, Alina M.
PY - 2011
Y1 - 2011
N2 - It is well known and has been clearly demonstrated that temperature plays a significant role in cerebral physiology and physiopathology, particularly in the setting of cardiac surgery with cardiopulmonary bypass (CPB). The human central nervous system (CNS) receives about 15% of the resting cardiac output and consumes about 20% of the oxygen required by the body at rest. The brain, which accounts for 2% of the total body weight, has an oxygen consumption of about 3.5 mL-1·100 g-1·min-1. This high metabolic rate mandates a high blood flow; therefore, cerebral blood flow (CBF) (Fig. 13.1) is of paramount importance and is normally under metabolic, neural, myogenic, and chemical control.1
AB - It is well known and has been clearly demonstrated that temperature plays a significant role in cerebral physiology and physiopathology, particularly in the setting of cardiac surgery with cardiopulmonary bypass (CPB). The human central nervous system (CNS) receives about 15% of the resting cardiac output and consumes about 20% of the oxygen required by the body at rest. The brain, which accounts for 2% of the total body weight, has an oxygen consumption of about 3.5 mL-1·100 g-1·min-1. This high metabolic rate mandates a high blood flow; therefore, cerebral blood flow (CBF) (Fig. 13.1) is of paramount importance and is normally under metabolic, neural, myogenic, and chemical control.1
UR - http://www.scopus.com/inward/record.url?scp=84892215101&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84892215101&partnerID=8YFLogxK
U2 - 10.1007/978-1-84996-293-3_13
DO - 10.1007/978-1-84996-293-3_13
M3 - Chapter
AN - SCOPUS:84892215101
SN - 9781849962926
SP - 141
EP - 157
BT - Brain Protection in Cardiac Surgery
PB - Springer London
ER -