Techniques for intraoperative radiation therapy for early-stage breast carcinoma

Daniel Trifiletti, Ryan Jones, Shayna L. Showalter, Bruce B. Libby, David R. Brenin, Anneke Schroen, Monica M. Morris, Kelli A. Reardon, Timothy N. Showalter

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Intraoperative radiation therapy (IORT) is a method of accelerated partial breast irradiation developed to replace other longer courses of radiotherapy with a single radiation session administered at the time of breast-conserving surgery. The purpose of this review is to summarize the advantages and disadvantages of breast IORT techniques that are currently available, as well to consider potential alternative techniques for breast IORT or ultra-short course breast radiotherapy. Furthermore, we highlight the published outcomes for the IORT treatment approaches including: electron therapy, superficial photon therapy and other techniques. Potential future directions of IORT are explored including novel IORT techniques utilizing intraoperative brachytherapy with in-room imaging and rapid treatment planning.

Original languageEnglish (US)
Pages (from-to)1047-1058
Number of pages12
JournalFuture Oncology
Volume11
Issue number7
DOIs
StatePublished - Apr 1 2015
Externally publishedYes

Fingerprint

Radiotherapy
Breast Neoplasms
Breast
Segmental Mastectomy
Brachytherapy
Therapeutics
Photons
Electrons
Radiation

Keywords

  • APBI
  • brachytherapy
  • breast
  • intraoperative
  • IORT
  • summary

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Trifiletti, D., Jones, R., Showalter, S. L., Libby, B. B., Brenin, D. R., Schroen, A., ... Showalter, T. N. (2015). Techniques for intraoperative radiation therapy for early-stage breast carcinoma. Future Oncology, 11(7), 1047-1058. https://doi.org/10.2217/fon.15.26

Techniques for intraoperative radiation therapy for early-stage breast carcinoma. / Trifiletti, Daniel; Jones, Ryan; Showalter, Shayna L.; Libby, Bruce B.; Brenin, David R.; Schroen, Anneke; Morris, Monica M.; Reardon, Kelli A.; Showalter, Timothy N.

In: Future Oncology, Vol. 11, No. 7, 01.04.2015, p. 1047-1058.

Research output: Contribution to journalReview article

Trifiletti, D, Jones, R, Showalter, SL, Libby, BB, Brenin, DR, Schroen, A, Morris, MM, Reardon, KA & Showalter, TN 2015, 'Techniques for intraoperative radiation therapy for early-stage breast carcinoma', Future Oncology, vol. 11, no. 7, pp. 1047-1058. https://doi.org/10.2217/fon.15.26
Trifiletti D, Jones R, Showalter SL, Libby BB, Brenin DR, Schroen A et al. Techniques for intraoperative radiation therapy for early-stage breast carcinoma. Future Oncology. 2015 Apr 1;11(7):1047-1058. https://doi.org/10.2217/fon.15.26
Trifiletti, Daniel ; Jones, Ryan ; Showalter, Shayna L. ; Libby, Bruce B. ; Brenin, David R. ; Schroen, Anneke ; Morris, Monica M. ; Reardon, Kelli A. ; Showalter, Timothy N. / Techniques for intraoperative radiation therapy for early-stage breast carcinoma. In: Future Oncology. 2015 ; Vol. 11, No. 7. pp. 1047-1058.
@article{52444fb7d8994a6ca3db517463c2dcf6,
title = "Techniques for intraoperative radiation therapy for early-stage breast carcinoma",
abstract = "Intraoperative radiation therapy (IORT) is a method of accelerated partial breast irradiation developed to replace other longer courses of radiotherapy with a single radiation session administered at the time of breast-conserving surgery. The purpose of this review is to summarize the advantages and disadvantages of breast IORT techniques that are currently available, as well to consider potential alternative techniques for breast IORT or ultra-short course breast radiotherapy. Furthermore, we highlight the published outcomes for the IORT treatment approaches including: electron therapy, superficial photon therapy and other techniques. Potential future directions of IORT are explored including novel IORT techniques utilizing intraoperative brachytherapy with in-room imaging and rapid treatment planning.",
keywords = "APBI, brachytherapy, breast, intraoperative, IORT, summary",
author = "Daniel Trifiletti and Ryan Jones and Showalter, {Shayna L.} and Libby, {Bruce B.} and Brenin, {David R.} and Anneke Schroen and Morris, {Monica M.} and Reardon, {Kelli A.} and Showalter, {Timothy N.}",
year = "2015",
month = "4",
day = "1",
doi = "10.2217/fon.15.26",
language = "English (US)",
volume = "11",
pages = "1047--1058",
journal = "Future Oncology",
issn = "1479-6694",
publisher = "Future Medicine Ltd.",
number = "7",

}

TY - JOUR

T1 - Techniques for intraoperative radiation therapy for early-stage breast carcinoma

AU - Trifiletti, Daniel

AU - Jones, Ryan

AU - Showalter, Shayna L.

AU - Libby, Bruce B.

AU - Brenin, David R.

AU - Schroen, Anneke

AU - Morris, Monica M.

AU - Reardon, Kelli A.

AU - Showalter, Timothy N.

PY - 2015/4/1

Y1 - 2015/4/1

N2 - Intraoperative radiation therapy (IORT) is a method of accelerated partial breast irradiation developed to replace other longer courses of radiotherapy with a single radiation session administered at the time of breast-conserving surgery. The purpose of this review is to summarize the advantages and disadvantages of breast IORT techniques that are currently available, as well to consider potential alternative techniques for breast IORT or ultra-short course breast radiotherapy. Furthermore, we highlight the published outcomes for the IORT treatment approaches including: electron therapy, superficial photon therapy and other techniques. Potential future directions of IORT are explored including novel IORT techniques utilizing intraoperative brachytherapy with in-room imaging and rapid treatment planning.

AB - Intraoperative radiation therapy (IORT) is a method of accelerated partial breast irradiation developed to replace other longer courses of radiotherapy with a single radiation session administered at the time of breast-conserving surgery. The purpose of this review is to summarize the advantages and disadvantages of breast IORT techniques that are currently available, as well to consider potential alternative techniques for breast IORT or ultra-short course breast radiotherapy. Furthermore, we highlight the published outcomes for the IORT treatment approaches including: electron therapy, superficial photon therapy and other techniques. Potential future directions of IORT are explored including novel IORT techniques utilizing intraoperative brachytherapy with in-room imaging and rapid treatment planning.

KW - APBI

KW - brachytherapy

KW - breast

KW - intraoperative

KW - IORT

KW - summary

UR - http://www.scopus.com/inward/record.url?scp=84925818409&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84925818409&partnerID=8YFLogxK

U2 - 10.2217/fon.15.26

DO - 10.2217/fon.15.26

M3 - Review article

C2 - 25804120

AN - SCOPUS:84925818409

VL - 11

SP - 1047

EP - 1058

JO - Future Oncology

JF - Future Oncology

SN - 1479-6694

IS - 7

ER -