Targeting the hypoxia pathway to treat pancreatic cancer

Lori A. Erickson, W. Edward Highsmith, Peiwen Fei, Jun Zhang

Research output: Contribution to journalComment/debate

19 Scopus citations

Abstract

The correlation between hypoxia and pancreatic cancer has long been discussed. Hao’s research team made many efforts on revealing the oncogenic function of hypoxic inducible factor-1 (HIF-1) in pancreatic cancer progression and development in recent years. Based on their research, they linked micro-environmental regulation of pancreatic cancer and its clinical significance. Hao’s research team suggests it is a promising approach to target HIF-1 for the management of pancreatic cancer progression and invasion.

Original languageEnglish (US)
Pages (from-to)2029-2031
Number of pages3
JournalDrug Design, Development and Therapy
Volume9
DOIs
StatePublished - Apr 8 2015

Keywords

  • HIF-1
  • Hypoxia
  • Pancreatic cancer

ASJC Scopus subject areas

  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery

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  • Cite this

    Erickson, L. A., Edward Highsmith, W., Fei, P., & Zhang, J. (2015). Targeting the hypoxia pathway to treat pancreatic cancer. Drug Design, Development and Therapy, 9, 2029-2031. https://doi.org/10.2147/DDDT.S80888