Tap-induced blink reflex and central nervous system dysfunction in diabetics with hyperosmolality

Y. Tachibana, A. Yasuhara, M. Ross

Research output: Contribution to journalArticle

1 Scopus citations


We studied the effect of hyperosmolality on the tap-induced blink reflex (TBR) in patients with diabetes. The TBR, consisting of R1 and R2 components, was either absent or delayed in patients compared to controls. The abnormalities correlated better with the degree of hyperosmolality than with the level of blood glucose. TBR was usually absent in unconscious patients with greatly elevated serum osmolality. In some patients with similar elevations in serum osmolality the R2' component was absent at a time when consciousness was preserved. Hence, TBR may be useful in monitoring CNS dysfunction in diabetics with hyperosmolality.

Original languageEnglish (US)
Pages (from-to)145-148
Number of pages4
JournalEuropean Neurology
Issue number3
StatePublished - Jan 1 1990



  • Blink reflex
  • Diabetes mellitus
  • Hyperosmolality
  • Tap stimulation

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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