Abstract
Takotsubo cardiomyopathy is an important differential diagnosis of acute coronary syndrome. It is characterized by normal (or near-normal) coronary arteries, regional wall motion abnormalities that extend beyond a single coronary vascular bed, and often, a precipitating stressor. Variants of the classical left ventricular apical ballooning, including mid- or basal left ventricular wall motion abnormalities, are increasingly recognized. Takotsubo cardiomyopathy is not rare, and heightened awareness of this unique cardiomyopathy likely will lead to a higher reported incidence. Diagnosis of takotsubo cardiomyopathy has important implications for clinical management at presentation and afterward. The long-term prognosis is generally favorable; however, a small subset has potentially life-threatening complications during the initial presentation. The pathophysiologic mechanism is unknown, but catecholamine excess likely has a central role.
Original language | English (US) |
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Pages (from-to) | 641-649 |
Number of pages | 9 |
Journal | JACC: Cardiovascular Imaging |
Volume | 3 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2010 |
Keywords
- acute coronary syndrome
- apical ballooning
- stress-induced cardiomyopathy
- takotsubo cardiomyopathy
- transient ventricular ballooning syndrome
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine