Takotsubo cardiomyopathy: A unique cardiomyopathy with variable ventricular morphology

R. Todd Hurst, Abhiram Prasad, J. Wells Askew, Partho P. Sengupta, A. Jamil Tajik

Research output: Contribution to journalReview articlepeer-review

155 Scopus citations

Abstract

Takotsubo cardiomyopathy is an important differential diagnosis of acute coronary syndrome. It is characterized by normal (or near-normal) coronary arteries, regional wall motion abnormalities that extend beyond a single coronary vascular bed, and often, a precipitating stressor. Variants of the classical left ventricular apical ballooning, including mid- or basal left ventricular wall motion abnormalities, are increasingly recognized. Takotsubo cardiomyopathy is not rare, and heightened awareness of this unique cardiomyopathy likely will lead to a higher reported incidence. Diagnosis of takotsubo cardiomyopathy has important implications for clinical management at presentation and afterward. The long-term prognosis is generally favorable; however, a small subset has potentially life-threatening complications during the initial presentation. The pathophysiologic mechanism is unknown, but catecholamine excess likely has a central role.

Original languageEnglish (US)
Pages (from-to)641-649
Number of pages9
JournalJACC: Cardiovascular Imaging
Volume3
Issue number6
DOIs
StatePublished - Jun 2010

Keywords

  • acute coronary syndrome
  • apical ballooning
  • stress-induced cardiomyopathy
  • takotsubo cardiomyopathy
  • transient ventricular ballooning syndrome

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Takotsubo cardiomyopathy: A unique cardiomyopathy with variable ventricular morphology'. Together they form a unique fingerprint.

Cite this