Takotsubo cardiomyopathy: A unique cardiomyopathy with variable ventricular morphology

R. Todd Hurst, Abhiram Prasad, J. Wells Askew, Partho P. Sengupta, A. Jamil Tajik

Research output: Contribution to journalArticle

143 Citations (Scopus)

Abstract

Takotsubo cardiomyopathy is an important differential diagnosis of acute coronary syndrome. It is characterized by normal (or near-normal) coronary arteries, regional wall motion abnormalities that extend beyond a single coronary vascular bed, and often, a precipitating stressor. Variants of the classical left ventricular apical ballooning, including mid- or basal left ventricular wall motion abnormalities, are increasingly recognized. Takotsubo cardiomyopathy is not rare, and heightened awareness of this unique cardiomyopathy likely will lead to a higher reported incidence. Diagnosis of takotsubo cardiomyopathy has important implications for clinical management at presentation and afterward. The long-term prognosis is generally favorable; however, a small subset has potentially life-threatening complications during the initial presentation. The pathophysiologic mechanism is unknown, but catecholamine excess likely has a central role.

Original languageEnglish (US)
Pages (from-to)641-649
Number of pages9
JournalJACC: Cardiovascular Imaging
Volume3
Issue number6
DOIs
StatePublished - Jun 2010

Fingerprint

Takotsubo Cardiomyopathy
Cardiomyopathies
Acute Coronary Syndrome
Catecholamines
Blood Vessels
Coronary Vessels
Differential Diagnosis
Incidence

Keywords

  • acute coronary syndrome
  • apical ballooning
  • stress-induced cardiomyopathy
  • takotsubo cardiomyopathy
  • transient ventricular ballooning syndrome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Takotsubo cardiomyopathy : A unique cardiomyopathy with variable ventricular morphology. / Hurst, R. Todd; Prasad, Abhiram; Askew, J. Wells; Sengupta, Partho P.; Tajik, A. Jamil.

In: JACC: Cardiovascular Imaging, Vol. 3, No. 6, 06.2010, p. 641-649.

Research output: Contribution to journalArticle

Hurst, R. Todd ; Prasad, Abhiram ; Askew, J. Wells ; Sengupta, Partho P. ; Tajik, A. Jamil. / Takotsubo cardiomyopathy : A unique cardiomyopathy with variable ventricular morphology. In: JACC: Cardiovascular Imaging. 2010 ; Vol. 3, No. 6. pp. 641-649.
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