Systemic Mastocytosis. Disease Overview, Pathogenesis, and Treatment

Animesh Pardanani

doi:10.1016/j.hoc.2012.08.001

Systemic Mastocytosis. Disease Overview, Pathogenesis, and Treatment

Animesh Pardanani

Hematology

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

The clinical presentation of mastocytosis is diverse, and patients may not fit the classical description. Diagnosis requires a bone marrow examination, including immunohistochemical stains for mast cell tryptase or CD117. The treatment of adult systemic mastocytosis is highly individualized. This article presents an overview of systemic mastocytosis and describes its pathogenesis and treatment.

Original language	English (US)
Pages (from-to)	1117-1128
Number of pages	12
Journal	Hematology/Oncology Clinics of North America
Volume	26
Issue number	5
DOIs	https://doi.org/10.1016/j.hoc.2012.08.001
State	Published - Oct 2012

Keywords

KITD816V
Mast cell disease
Myeloproliferative neoplasm

ASJC Scopus subject areas

Hematology
Oncology

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10.1016/j.hoc.2012.08.001

Cite this

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title = "Systemic Mastocytosis. Disease Overview, Pathogenesis, and Treatment",

abstract = "The clinical presentation of mastocytosis is diverse, and patients may not fit the classical description. Diagnosis requires a bone marrow examination, including immunohistochemical stains for mast cell tryptase or CD117. The treatment of adult systemic mastocytosis is highly individualized. This article presents an overview of systemic mastocytosis and describes its pathogenesis and treatment.",

keywords = "KITD816V, Mast cell disease, Myeloproliferative neoplasm",

author = "Animesh Pardanani",

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language = "English (US)",

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AB - The clinical presentation of mastocytosis is diverse, and patients may not fit the classical description. Diagnosis requires a bone marrow examination, including immunohistochemical stains for mast cell tryptase or CD117. The treatment of adult systemic mastocytosis is highly individualized. This article presents an overview of systemic mastocytosis and describes its pathogenesis and treatment.

KW - KITD816V

KW - Mast cell disease

KW - Myeloproliferative neoplasm

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DO - 10.1016/j.hoc.2012.08.001

M3 - Review article

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SN - 0889-8588

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JO - Hematology/Oncology Clinics of North America

JF - Hematology/Oncology Clinics of North America

IS - 5

ER -

Systemic Mastocytosis. Disease Overview, Pathogenesis, and Treatment

Abstract

Keywords

ASJC Scopus subject areas

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