Systemic Mastocytosis. Disease Overview, Pathogenesis, and Treatment

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The clinical presentation of mastocytosis is diverse, and patients may not fit the classical description. Diagnosis requires a bone marrow examination, including immunohistochemical stains for mast cell tryptase or CD117. The treatment of adult systemic mastocytosis is highly individualized. This article presents an overview of systemic mastocytosis and describes its pathogenesis and treatment.

Original languageEnglish (US)
Pages (from-to)1117-1128
Number of pages12
JournalHematology/Oncology Clinics of North America
Volume26
Issue number5
DOIs
StatePublished - Oct 2012

Fingerprint

Systemic Mastocytosis
Mastocytosis
Bone Marrow Examination
Tryptases
Coloring Agents
Therapeutics

Keywords

  • KITD816V
  • Mast cell disease
  • Myeloproliferative neoplasm

ASJC Scopus subject areas

  • Oncology
  • Hematology

Cite this

Systemic Mastocytosis. Disease Overview, Pathogenesis, and Treatment. / Pardanani, Animesh D.

In: Hematology/Oncology Clinics of North America, Vol. 26, No. 5, 10.2012, p. 1117-1128.

Research output: Contribution to journalArticle

@article{5a1820f13a8245f2aa55544e13cccbc3,
title = "Systemic Mastocytosis. Disease Overview, Pathogenesis, and Treatment",
abstract = "The clinical presentation of mastocytosis is diverse, and patients may not fit the classical description. Diagnosis requires a bone marrow examination, including immunohistochemical stains for mast cell tryptase or CD117. The treatment of adult systemic mastocytosis is highly individualized. This article presents an overview of systemic mastocytosis and describes its pathogenesis and treatment.",
keywords = "KITD816V, Mast cell disease, Myeloproliferative neoplasm",
author = "Pardanani, {Animesh D}",
year = "2012",
month = "10",
doi = "10.1016/j.hoc.2012.08.001",
language = "English (US)",
volume = "26",
pages = "1117--1128",
journal = "Hematology/Oncology Clinics of North America",
issn = "0889-8588",
publisher = "W.B. Saunders Ltd",
number = "5",

}

TY - JOUR

T1 - Systemic Mastocytosis. Disease Overview, Pathogenesis, and Treatment

AU - Pardanani, Animesh D

PY - 2012/10

Y1 - 2012/10

N2 - The clinical presentation of mastocytosis is diverse, and patients may not fit the classical description. Diagnosis requires a bone marrow examination, including immunohistochemical stains for mast cell tryptase or CD117. The treatment of adult systemic mastocytosis is highly individualized. This article presents an overview of systemic mastocytosis and describes its pathogenesis and treatment.

AB - The clinical presentation of mastocytosis is diverse, and patients may not fit the classical description. Diagnosis requires a bone marrow examination, including immunohistochemical stains for mast cell tryptase or CD117. The treatment of adult systemic mastocytosis is highly individualized. This article presents an overview of systemic mastocytosis and describes its pathogenesis and treatment.

KW - KITD816V

KW - Mast cell disease

KW - Myeloproliferative neoplasm

UR - http://www.scopus.com/inward/record.url?scp=84866609437&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866609437&partnerID=8YFLogxK

U2 - 10.1016/j.hoc.2012.08.001

DO - 10.1016/j.hoc.2012.08.001

M3 - Article

VL - 26

SP - 1117

EP - 1128

JO - Hematology/Oncology Clinics of North America

JF - Hematology/Oncology Clinics of North America

SN - 0889-8588

IS - 5

ER -