Systemic chemotherapy in patients with renal failure

Lishan Bekele, Marieberta Vidal Vazquez, Alex Adjei

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The administration of systemic chemotherapy to patients with moderate-to-severe organ impairment remains a challenge. In renal failure, guidelines for dose adjustments exist for very few chemotherapy agents. Subsequently, oncologists typically withhold treatment with systemic chemotherapy for patients with severe renal dysfunction. We present the case of a patient with metastatic transitional cell carcinoma of the bladder and renal failure who underwent successful systemic chemotherapy with paclitaxel and carboplatin. The data on systemic chemotherapy in patients with severe renal dysfunction are reviewed.

Original languageEnglish (US)
Pages (from-to)382-384
Number of pages3
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Volume24
Issue number4
DOIs
StatePublished - Aug 20 2001

Fingerprint

Renal Insufficiency
Drug Therapy
Kidney
Transitional Cell Carcinoma
Carboplatin
Paclitaxel
Urinary Bladder
Guidelines
Therapeutics

Keywords

  • Bladder cancer
  • Carboplatin
  • Chemotherapy
  • Paclitaxel
  • Renal failure

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Systemic chemotherapy in patients with renal failure. / Bekele, Lishan; Vidal Vazquez, Marieberta; Adjei, Alex.

In: American Journal of Clinical Oncology: Cancer Clinical Trials, Vol. 24, No. 4, 20.08.2001, p. 382-384.

Research output: Contribution to journalArticle

Bekele, Lishan ; Vidal Vazquez, Marieberta ; Adjei, Alex. / Systemic chemotherapy in patients with renal failure. In: American Journal of Clinical Oncology: Cancer Clinical Trials. 2001 ; Vol. 24, No. 4. pp. 382-384.
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