TY - JOUR
T1 - Systematic review
T2 - Transient left ventricular apical ballooning: A syndrome that mimics ST-segment elevation myocardial infarction
AU - Bybee, Kevin A.
AU - Kara, Tomas
AU - Prasad, Abhiram
AU - Lerman, Amir
AU - Barsness, Greg W.
AU - Scott Wright, R.
AU - Rihal, Charanjit S.
PY - 2004/12/7
Y1 - 2004/12/7
N2 - The transient left ventricular apical ballooning syndrome, also known as takotsubo cardiomyopathy, is characterized by transient wall-motion abnormalities involving the left ventricular apex and mid-ventricle in the absence of obstructive epicardial coronary disease. In this paper, we review case series that report on patients with the transient left ventricular apical ballooning syndrome to better characterize patients presenting with the syndrome. We identified 7 case series that reported on at least 5 consecutive patients with the transient left ventricular apical ballooning syndrome. The syndrome more often affects postmenopausal women (82% to 100%) (mean age, 62 to 75 years). Patients commonly present with ST-segment elevation in the precordial leads, chest pain, relatively minor elevation of cardiac enzyme and biomarker levels, and transient apical systolic left ventricular dysfunction despite the absence of obstructive epicardial coronary disease. An episode of emotional or physiologic stress frequently precedes presentation with the syndrome. The in-hospital mortality rate seems to be low, as does the risk for recurrence.
AB - The transient left ventricular apical ballooning syndrome, also known as takotsubo cardiomyopathy, is characterized by transient wall-motion abnormalities involving the left ventricular apex and mid-ventricle in the absence of obstructive epicardial coronary disease. In this paper, we review case series that report on patients with the transient left ventricular apical ballooning syndrome to better characterize patients presenting with the syndrome. We identified 7 case series that reported on at least 5 consecutive patients with the transient left ventricular apical ballooning syndrome. The syndrome more often affects postmenopausal women (82% to 100%) (mean age, 62 to 75 years). Patients commonly present with ST-segment elevation in the precordial leads, chest pain, relatively minor elevation of cardiac enzyme and biomarker levels, and transient apical systolic left ventricular dysfunction despite the absence of obstructive epicardial coronary disease. An episode of emotional or physiologic stress frequently precedes presentation with the syndrome. The in-hospital mortality rate seems to be low, as does the risk for recurrence.
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U2 - 10.7326/0003-4819-141-11-200412070-00010
DO - 10.7326/0003-4819-141-11-200412070-00010
M3 - Review article
C2 - 15583228
AN - SCOPUS:10044225734
SN - 0003-4819
VL - 141
SP - 858
EP - 865
JO - Annals of internal medicine
JF - Annals of internal medicine
IS - 11
ER -