Synthesis of (S)- and (R)-enantiomers of p-(4- hydroxybenzoyl)phenylalanine, useful photoaffinity labeling probes for peptide-protein binding sites

Abdul H. Fauq, Chewki Ziani-Cherif, Elliott Richelson

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

A high yield, multigram synthesis of both enantiomers of p-(4- hydroxybenzoyl)phenylalanine, cross-linking probes for peptide-protein binding interactions, is reported. The synthesis was accomplished using Schollkopf chiral auxiliary reagents.

Original languageEnglish (US)
Pages (from-to)2333-2338
Number of pages6
JournalTetrahedron Asymmetry
Volume9
Issue number13
DOIs
StatePublished - Jul 3 1998

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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