Abstract
The synthesis of 10,10′,19,19,19,19′,19′,19′‐2H8‐β‐carotene is described. The double condensation (C15+C10+C15=C40) of the Wittig salt of 9,9,9,10‐2H4‐β‐ionylidene ethanol with the symmetrical C10 dial 2,7‐dimethyl‐2,4,6‐octatrienedial led directly to 2H8‐β‐carotene. The symmetrical labelling pattern of this deuterated β‐carotene will function as a tracer for the study of β‐carotene metabolism in humans.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 783-788 |
| Number of pages | 6 |
| Journal | Journal of Labelled Compounds and Radiopharmaceuticals |
| Volume | 27 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1989 |
Keywords
- 10,10′,19,19,19,19′,19′,19′‐H‐β‐carotene
- 9,9,9,10‐H‐β‐ionylidene ethanol
- 9,9,9,10‐H‐β‐ionylideneethyl triphenyl phosphonium bromide
- Deuterated β‐carotene
- carotenoid synthesis
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Radiology Nuclear Medicine and imaging
- Drug Discovery
- Spectroscopy
- Organic Chemistry