Synthesis and 2D NMR analysis of a cyclopropane containing analogue of huperzine A

Alan P. Kozikowski, Fumio Yamada, Yuan-Ping Pang

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

In order to probe the possible binding site in acetylcholinesterase for huperzine A, a cyclopropane bearing analogue of huperzine A was synthesized, and the stereochemistry of this compound was established by NMR experiments.

Original languageEnglish (US)
Pages (from-to)2653-2656
Number of pages4
JournalTetrahedron Letters
Volume33
Issue number19
DOIs
StatePublished - May 5 1992

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Bearings (structural)
Nuclear magnetic resonance
Stereochemistry
Acetylcholinesterase
Binding Sites
Experiments
huperzine A
cyclopropane

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis and 2D NMR analysis of a cyclopropane containing analogue of huperzine A. / Kozikowski, Alan P.; Yamada, Fumio; Pang, Yuan-Ping.

In: Tetrahedron Letters, Vol. 33, No. 19, 05.05.1992, p. 2653-2656.

Research output: Contribution to journalArticle

Kozikowski, Alan P. ; Yamada, Fumio ; Pang, Yuan-Ping. / Synthesis and 2D NMR analysis of a cyclopropane containing analogue of huperzine A. In: Tetrahedron Letters. 1992 ; Vol. 33, No. 19. pp. 2653-2656.
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