Pokeweed antiviral protein (PAP), in combination with either guanidine or ribavirin, exhibited both synergy and antagonism toward the replication of Newcastle disease virus, low, medium, and high effective concentrations of both PAP and guanidine were synergistic when used in combination. High effective concentrations of ribavirin in combination with PAP were antagonistic, whereas low and medium effective concentrations were synergistic.
- Newcastle disease virus
- Pokeweed antiviral protein
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)