Symptom profiles in children with ADHD: Effects of comorbidity and gender

Jeffrey H. Newcorn, Jeffrey M. Halperin, Peter S. Jensen, Howard B. Abikoff, L. Eugene Arnold, Dennis P. Cantwell, C. Keith Conners, Glen R. Elliott, Jeffrey N. Epstein, Laurence L. Greenhill, Lily Hechtman, Stephen P. Hinshaw, Betsy Hoza, Helena C. Kraemer, William E. Pelham, Joanne B. Severe, James M. Swanson, Karen C. Wells, Timothy Wigal, Benedetto Vitiello

Research output: Contribution to journalArticle

269 Citations (Scopus)

Abstract

Objective: To examine ratings and objective measures of attention-deficit/hyperactivity disorder (ADHD) symptoms to assess whether ADHD children with add without comorbid conditions have equally high levels of core symptoms and whether symptom profiles differ as a function of comorbidity and gender. Method: Four hundred ninety-eight children from the NIMH Collaborative Multisite Multimodal Treatment Study of Children With Attention-Deficit/Hyperactivity Disorder (MTA) were divided into comorbid groups based on the parent Diagnostic Interview Schedule for. Children and assessed via parents' and teachers' Swanson, Nolan, and Pelham (SNAP) ratings and a continuous performance test (CPT). Comorbidity and gender effects were examined using analyses of covariance controlled for age and site. Results: CPT inattention, impulsivity, and dyscontrol errors were high in all ADHD groups. Children with ADHD + oppositional defiant or conduct disorder were rated as more impulsive than inattentive, while children with ADHD + anxiety disorders (ANX) were relatively more inattentive than impulsive. Girls were less impaired than boys on most ratings and several CPT indices, particularly impulsivity, and girls with ADHD + ANX made fewer CPT impulsivity errors than girls with ADHD-only. Conclusions: Children with ADHD have high levels of core symptoms as measured by rating scales and CPT, irrespective of comorbidity. However, there are important differences in symptomatology as a function of comorbidity and gender.

Original languageEnglish (US)
Pages (from-to)137-146
Number of pages10
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume40
Issue number2
StatePublished - 2001
Externally publishedYes

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Attention Deficit Disorder with Hyperactivity
Comorbidity
Impulsive Behavior
Anxiety Disorders
Pemetrexed
Attention Deficit and Disruptive Behavior Disorders
National Institute of Mental Health (U.S.)
Conduct Disorder
Combined Modality Therapy
Appointments and Schedules
Parents
Interviews

Keywords

  • Attention-deficit/hyperactivity disorder
  • Comorbidity
  • Gender
  • Impulsivity

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Developmental and Educational Psychology

Cite this

Newcorn, J. H., Halperin, J. M., Jensen, P. S., Abikoff, H. B., Arnold, L. E., Cantwell, D. P., ... Vitiello, B. (2001). Symptom profiles in children with ADHD: Effects of comorbidity and gender. Journal of the American Academy of Child and Adolescent Psychiatry, 40(2), 137-146.

Symptom profiles in children with ADHD : Effects of comorbidity and gender. / Newcorn, Jeffrey H.; Halperin, Jeffrey M.; Jensen, Peter S.; Abikoff, Howard B.; Arnold, L. Eugene; Cantwell, Dennis P.; Conners, C. Keith; Elliott, Glen R.; Epstein, Jeffrey N.; Greenhill, Laurence L.; Hechtman, Lily; Hinshaw, Stephen P.; Hoza, Betsy; Kraemer, Helena C.; Pelham, William E.; Severe, Joanne B.; Swanson, James M.; Wells, Karen C.; Wigal, Timothy; Vitiello, Benedetto.

In: Journal of the American Academy of Child and Adolescent Psychiatry, Vol. 40, No. 2, 2001, p. 137-146.

Research output: Contribution to journalArticle

Newcorn, JH, Halperin, JM, Jensen, PS, Abikoff, HB, Arnold, LE, Cantwell, DP, Conners, CK, Elliott, GR, Epstein, JN, Greenhill, LL, Hechtman, L, Hinshaw, SP, Hoza, B, Kraemer, HC, Pelham, WE, Severe, JB, Swanson, JM, Wells, KC, Wigal, T & Vitiello, B 2001, 'Symptom profiles in children with ADHD: Effects of comorbidity and gender', Journal of the American Academy of Child and Adolescent Psychiatry, vol. 40, no. 2, pp. 137-146.
Newcorn JH, Halperin JM, Jensen PS, Abikoff HB, Arnold LE, Cantwell DP et al. Symptom profiles in children with ADHD: Effects of comorbidity and gender. Journal of the American Academy of Child and Adolescent Psychiatry. 2001;40(2):137-146.
Newcorn, Jeffrey H. ; Halperin, Jeffrey M. ; Jensen, Peter S. ; Abikoff, Howard B. ; Arnold, L. Eugene ; Cantwell, Dennis P. ; Conners, C. Keith ; Elliott, Glen R. ; Epstein, Jeffrey N. ; Greenhill, Laurence L. ; Hechtman, Lily ; Hinshaw, Stephen P. ; Hoza, Betsy ; Kraemer, Helena C. ; Pelham, William E. ; Severe, Joanne B. ; Swanson, James M. ; Wells, Karen C. ; Wigal, Timothy ; Vitiello, Benedetto. / Symptom profiles in children with ADHD : Effects of comorbidity and gender. In: Journal of the American Academy of Child and Adolescent Psychiatry. 2001 ; Vol. 40, No. 2. pp. 137-146.
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