Sympathetic vasodilatation in human limbs

Michael Joseph Joyner, J. R. Halliwill

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

This review focuses on recent developments in our understanding of active vasodilatation in human skin and skeletal muscle. We have attempted to place recent advances in their historical context and review the evolution of thinking on active vasodilatation in these two vascular beds. In human skin, active vasodilatation is well established, but the neurotransmitter responsible for the dilatation is unknown. In human skeletal muscle, older studies provided circumstantial evidence consistent with sympathetically mediated vasodilatation, but the evidence was never unambiguous. By contrast, recent studies on active vasodilatation in human skeletal muscle in conjunction with a reinterpretation of data from previous studies casts doubt on the existence of sympathetic vasodilator fibres in human skeletal muscle.

Original languageEnglish (US)
Pages (from-to)471-480
Number of pages10
JournalJournal of Physiology
Volume526
Issue number3
StatePublished - 2000

Fingerprint

Vasodilation
Extremities
Skeletal Muscle
Adrenergic Fibers
Skin
Vasodilator Agents
Neurotransmitter Agents
Blood Vessels
Dilatation

ASJC Scopus subject areas

  • Physiology

Cite this

Joyner, M. J., & Halliwill, J. R. (2000). Sympathetic vasodilatation in human limbs. Journal of Physiology, 526(3), 471-480.

Sympathetic vasodilatation in human limbs. / Joyner, Michael Joseph; Halliwill, J. R.

In: Journal of Physiology, Vol. 526, No. 3, 2000, p. 471-480.

Research output: Contribution to journalArticle

Joyner, MJ & Halliwill, JR 2000, 'Sympathetic vasodilatation in human limbs', Journal of Physiology, vol. 526, no. 3, pp. 471-480.
Joyner, Michael Joseph ; Halliwill, J. R. / Sympathetic vasodilatation in human limbs. In: Journal of Physiology. 2000 ; Vol. 526, No. 3. pp. 471-480.
@article{d534b16bb5c346bf93791ddd4e890264,
title = "Sympathetic vasodilatation in human limbs",
abstract = "This review focuses on recent developments in our understanding of active vasodilatation in human skin and skeletal muscle. We have attempted to place recent advances in their historical context and review the evolution of thinking on active vasodilatation in these two vascular beds. In human skin, active vasodilatation is well established, but the neurotransmitter responsible for the dilatation is unknown. In human skeletal muscle, older studies provided circumstantial evidence consistent with sympathetically mediated vasodilatation, but the evidence was never unambiguous. By contrast, recent studies on active vasodilatation in human skeletal muscle in conjunction with a reinterpretation of data from previous studies casts doubt on the existence of sympathetic vasodilator fibres in human skeletal muscle.",
author = "Joyner, {Michael Joseph} and Halliwill, {J. R.}",
year = "2000",
language = "English (US)",
volume = "526",
pages = "471--480",
journal = "Journal of Physiology",
issn = "0022-3751",
publisher = "Wiley-Blackwell",
number = "3",

}

TY - JOUR

T1 - Sympathetic vasodilatation in human limbs

AU - Joyner, Michael Joseph

AU - Halliwill, J. R.

PY - 2000

Y1 - 2000

N2 - This review focuses on recent developments in our understanding of active vasodilatation in human skin and skeletal muscle. We have attempted to place recent advances in their historical context and review the evolution of thinking on active vasodilatation in these two vascular beds. In human skin, active vasodilatation is well established, but the neurotransmitter responsible for the dilatation is unknown. In human skeletal muscle, older studies provided circumstantial evidence consistent with sympathetically mediated vasodilatation, but the evidence was never unambiguous. By contrast, recent studies on active vasodilatation in human skeletal muscle in conjunction with a reinterpretation of data from previous studies casts doubt on the existence of sympathetic vasodilator fibres in human skeletal muscle.

AB - This review focuses on recent developments in our understanding of active vasodilatation in human skin and skeletal muscle. We have attempted to place recent advances in their historical context and review the evolution of thinking on active vasodilatation in these two vascular beds. In human skin, active vasodilatation is well established, but the neurotransmitter responsible for the dilatation is unknown. In human skeletal muscle, older studies provided circumstantial evidence consistent with sympathetically mediated vasodilatation, but the evidence was never unambiguous. By contrast, recent studies on active vasodilatation in human skeletal muscle in conjunction with a reinterpretation of data from previous studies casts doubt on the existence of sympathetic vasodilator fibres in human skeletal muscle.

UR - http://www.scopus.com/inward/record.url?scp=0033845589&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033845589&partnerID=8YFLogxK

M3 - Article

VL - 526

SP - 471

EP - 480

JO - Journal of Physiology

JF - Journal of Physiology

SN - 0022-3751

IS - 3

ER -