Survivorship analysis in patients with periosteal chondrosarcoma

Panayiotis J. Papagelopoulos, Evanthia Galanis, Andreas F. Mavrogenis, Olga D. Savvidou, Jeffrey R. Bond, Krishnan K. Unni, Franklin H. Sim

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

To investigate outcome and identify prognostic factors, we retrospectively reviewed 24 consecutive patients with periosteal chondrosarcomas. There were 17 males and seven females with a mean age of 37.6 years (range, 15-73 years). The femur was involved in 12 patients, the proximal humerus in five, the tibia in two, and the distal fibula, ilium, pubis, metatarsal, and rib in one patient each. The mean greatest dimension of the lesions was 8.1 cm (range, 1.5-27 cm). Based on the histologic pattern, there were 18 Grade 1 tumors and six Grade 2 tumors. All patients were treated surgically. Two patients had intralesional excisions, five patients had marginal excisions, and 17 patients had wide resections. With a mean followup of 17 years (range, 28 months-47 years), seven of 24 patients (29%) had one or more local recurrences. The 5-year local recurrence-free survival was less in patients treated with intralesional or marginal excisions (25%) than for patients treated with wide resections (93%). At the latest followup, six of 24 patients (25%) had died of pulmonary metastases. The overall 5-year metastasis-free survival was 83%. The 5-year metastasis-free survival was less for patients with Grade 2 tumors (50%) than for patients with Grade 1 tumors (94%).

Original languageEnglish (US)
Pages (from-to)199-207
Number of pages9
JournalClinical Orthopaedics and Related Research
Issue number448
DOIs
StatePublished - Jul 2006

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Chondrosarcoma
Survival Rate
Neoplasm Metastasis
Survival
Neoplasms
Pubic Bone
Ilium
Recurrence
Fibula
Metatarsal Bones
Humerus
Ribs
Tibia
Femur

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Papagelopoulos, P. J., Galanis, E., Mavrogenis, A. F., Savvidou, O. D., Bond, J. R., Unni, K. K., & Sim, F. H. (2006). Survivorship analysis in patients with periosteal chondrosarcoma. Clinical Orthopaedics and Related Research, (448), 199-207. https://doi.org/10.1097/01.blo.0000194684.40624.a8

Survivorship analysis in patients with periosteal chondrosarcoma. / Papagelopoulos, Panayiotis J.; Galanis, Evanthia; Mavrogenis, Andreas F.; Savvidou, Olga D.; Bond, Jeffrey R.; Unni, Krishnan K.; Sim, Franklin H.

In: Clinical Orthopaedics and Related Research, No. 448, 07.2006, p. 199-207.

Research output: Contribution to journalArticle

Papagelopoulos, PJ, Galanis, E, Mavrogenis, AF, Savvidou, OD, Bond, JR, Unni, KK & Sim, FH 2006, 'Survivorship analysis in patients with periosteal chondrosarcoma', Clinical Orthopaedics and Related Research, no. 448, pp. 199-207. https://doi.org/10.1097/01.blo.0000194684.40624.a8
Papagelopoulos, Panayiotis J. ; Galanis, Evanthia ; Mavrogenis, Andreas F. ; Savvidou, Olga D. ; Bond, Jeffrey R. ; Unni, Krishnan K. ; Sim, Franklin H. / Survivorship analysis in patients with periosteal chondrosarcoma. In: Clinical Orthopaedics and Related Research. 2006 ; No. 448. pp. 199-207.
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